{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,13]],"date-time":"2025-12-13T07:00:35Z","timestamp":1765609235439,"version":"3.40.4"},"reference-count":5,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T00:00:00Z","timestamp":1072051200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,12,22]],"date-time":"2003-12-22T00:00:00Z","timestamp":1072051200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>&lt;i&gt;Aim:&lt;\/i&gt; To present the technique and efficiency of intravitreal recombinant tissue plasminogen activator (r-TPA) and gas injection in acute submacular hemorrhage (SMH) due to traumatic choroidal rupture. &lt;i&gt;Patients and Methods:&lt;\/i&gt; 0.4 ml of sulfur hexafluoride was injected into the vitreous cavity in 2 patients with SMH due to traumatic choroidal rupture. In 1 patient gas injection was combined with 50 \u00b5g r-TPA. Both patients were closely followed. &lt;i&gt;Results:&lt;\/i&gt; Preoperative visual acuity was 20\/125 in one eye and 20\/100 in the other. At the end of the follow-up, visual acuity had improved to 20\/32 in both eyes. &lt;i&gt;Conclusion:&lt;\/i&gt; r-TPA and gas injection into the vitreous body may be an efficient therapy in patients with submacular hemorrhage due to choroidal rupture.<\/jats:p>","DOI":"10.1159\/000074569","type":"journal-article","created":{"date-parts":[[2003,12,19]],"date-time":"2003-12-19T09:25:47Z","timestamp":1071825947000},"page":"64-69","source":"Crossref","is-referenced-by-count":16,"title":["Intravitreal r-TPA and Gas Injection in Traumatic Submacular Hemorrhage"],"prefix":"10.1159","volume":"218","author":[{"given":"Detlef","family":"Holland","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Burkhard","family":"Wiechens","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2003,12,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-10513"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s004170050232"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/s004170000156"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S0161-6420(99)90399-8"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9394(99)00474-2"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/74569","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/74569","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:54:13Z","timestamp":1745466853000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000074569"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,12,22]]},"references-count":5,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2004,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000074569","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"type":"print","value":"0030-3755"},{"type":"electronic","value":"1423-0267"}],"subject":[],"published":{"date-parts":[[2003,12,22]]}}}