{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,22]],"date-time":"2026-06-22T10:34:52Z","timestamp":1782124492439,"version":"3.54.5"},"reference-count":2,"publisher":"S. Karger AG","issue":"1-4","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Although gamma knife radiosurgery (GKRS) has been shown to be safe and effective for the treatment of trigeminal neuralgia (TN), there are few studies that report the results of a second GKRS. &lt;i&gt;Method:&lt;\/i&gt; Between May 22, 1998 and April 1, 2003, we treated 335 primary TN patients with GKRS. All received a maximum dose of 75 Gy to the cisternal trigeminal nerve. 45 patients with recurrent or persistent TN were treated with a maximum dose of 40 Gy at a second GKRS and were available for at least 6 months of follow-up. &lt;i&gt;Results:&lt;\/i&gt; Final pain relief (mean of 15 months after second GKRS) was 50% or greater in 28 of the 45 patients (62.2%). Patients who had no neurosurgical procedure prior to their first GKRS were more likely to have pain relief of 50% or greater following the second GKRS (p = 0.042). Significant new dysesthesias (score greater than 5 on a scale of 0\u201310) developed in 2 patients (4.4%). &lt;i&gt;Conclusion:&lt;\/i&gt; Repeat GKRS has a good chance of relieving TN pain without complications and is more likely to relieve pain in those who did not have any procedure prior to their first GKRS.<\/jats:p>","DOI":"10.1159\/000075103","type":"journal-article","created":{"date-parts":[[2004,1,30]],"date-time":"2004-01-30T09:31:09Z","timestamp":1075455069000},"page":"43-49","source":"Crossref","is-referenced-by-count":32,"title":["Repeat Gamma Knife Radiosurgery for Trigeminal Neuralgia"],"prefix":"10.1159","volume":"81","author":[{"given":"Ronald","family":"Brisman","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2004,1,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200206000-00015"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/00006123-200203000-00012"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/75103","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/75103","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:59:19Z","timestamp":1745467159000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000075103"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":2,"journal-issue":{"issue":"1-4","published-online":{"date-parts":[[2004,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000075103","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003]]}}}