{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:11:38Z","timestamp":1745554298517,"version":"3.40.4"},"reference-count":3,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2003,1,1]],"date-time":"2003-01-01T00:00:00Z","timestamp":1041379200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["ORL"],"published-print":{"date-parts":[[2003]]},"abstract":"<jats:p>&lt;i&gt;Hypothesis:&lt;\/i&gt; Any kind of depressed systemic anti-measles reaction can lead to the induction of a local immune response in the inner ear and possibly to reactivation of bone turnover in this region. &lt;i&gt;Methods:&lt;\/i&gt; Different dilutions of sera were tested for neutralizing activity against a constant viral concentration. The ability of measles virus to infect and replicate in the cell monolayer was detected by enumeration of living and growing cells with a colored reaction. &lt;i&gt;Results:&lt;\/i&gt; Virus-neutralizing activity in the sera of patients with confirmed otosclerosis was significantly weaker than in that of healthy controls. When age- and sex-matched pairs were compared, the neutralizing activity in the healthy counterpart was higher in 5 cases. Nearly complete viral neutralization was achieved with samples containing inactivated complement and in IgG-containing fractions, but not in immunoglobulin-depleted samples. &lt;i&gt;Conclusion:&lt;\/i&gt; The present study is consistent with measles virus participation at least in the initiation of some cases of otosclerosis.<\/jats:p>","DOI":"10.1159\/000075226","type":"journal-article","created":{"date-parts":[[2004,1,21]],"date-time":"2004-01-21T08:52:58Z","timestamp":1074675178000},"page":"279-283","source":"Crossref","is-referenced-by-count":2,"title":["Decreased Measles Virus-Neutralizing Activity in Sera from Otosclerotic Patients"],"prefix":"10.1159","volume":"65","author":[{"given":"Stephan","family":"Lolov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petya","family":"Zarzalanova","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Edrev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stanimir","family":"Kyurkchiev","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2004,1,22]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200111000-00009"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0022-1759(83)90303-4"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200103000-00023"}],"container-title":["ORL"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/75226","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/75226","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:00:19Z","timestamp":1745467219000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000075226"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003]]},"references-count":3,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2003,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000075226","archive":["Portico"],"relation":{},"ISSN":["0301-1569","1423-0275"],"issn-type":[{"type":"print","value":"0301-1569"},{"type":"electronic","value":"1423-0275"}],"subject":[],"published":{"date-parts":[[2003]]}}}