{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:42:31Z","timestamp":1791308551590,"version":"4.3.1"},"reference-count":6,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neuropsychobiology"],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>The electroencephalographic effects of two intravenous sedative\/hypnotic drugs, propofol and thiopental, were studied at three stable blood concentrations in 52 normal healthy volunteers. The higher concentration resulted in unresponsiveness (lack of response to auditory\/tactile stimuli) in all subjects. This report describes the strong frontal-central rhythms apparent in this state using a quantitative description of oscillatory systems underlying the rhythm. These rhythms occur when sedative drug concentrations are greater than those producing the well-described increase in broadband \u03b2-power associated with many sedative drugs. Propofol induces rhythms in the \u03b1-range, while thiopental produces rhythms in the \u03b2-range. Quasistationary for a period of about 1 h, these rhythms exceed the baseline \u03b1-rhythm in power. By their resonant nature, these propofol-induced rhythms are analogous to \u2018the classic \u03b1-rhythm\u2019, but quantitative characteristics of the underlying oscillatory systems are different. Baseline properties of the oscillatory system underlying the initial resting \u03b1-rhythm recover completely as drug concentration decays to negligible values.<\/jats:p>","DOI":"10.1159\/000079981","type":"journal-article","created":{"date-parts":[[2004,9,15]],"date-time":"2004-09-15T07:53:02Z","timestamp":1095234782000},"page":"257-266","source":"Crossref","is-referenced-by-count":138,"title":["Propofol-Induced Alpha Rhythm"],"prefix":"10.1159","volume":"50","author":[{"given":"Vladimir A.","family":"Feshchenko","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert A.","family":"Veselis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruth A.","family":"Reinsel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2004,9,14]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00004691-200107000-00005"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/86.3.354"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S1388-2457(00)00538-1"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1103\/PhysRevE.60.7299"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200110000-00018"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/17126"}],"container-title":["Neuropsychobiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/79981","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/79981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:29:59Z","timestamp":1745450999000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000079981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":6,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2004,9,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000079981","archive":["Portico"],"relation":{},"ISSN":["0302-282X","1423-0224"],"issn-type":[{"value":"0302-282X","type":"print"},{"value":"1423-0224","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004]]}}}