{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T18:34:45Z","timestamp":1790361285201,"version":"4.1.0"},"reference-count":13,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>This clinical study evaluated the effect of rinsing with an essential oil-containing antiseptic mouthrinse, with or without 100 mg\/kg fluoride ion, on the plaque metabolic acid production and plaque pH response after a sucrose challenge. This observer-blind, randomized study used a three-way crossover design. Twenty-four subjects rinsed with 20 ml of one of the following rinses: (1) essential oil (EO) mouthrinse, (2) essential oil mouthrinse plus 100\u00a0mg\/kg fluoride, or (3) negative control, for 30 s, twice daily for 16 days. On day 17, 1 h after the last mouthrinse, subjects rinsed with 20 ml of mass fraction 10% sucrose solution for 1 min. Seven minutes after the sucrose challenge, supragingival plaque was collected from molar and premolar teeth. Plaque pH and metabolic acid ions were analyzed using a micro pH electrode and capillary electrophoresis, respectively. The results showed that after EO mouthrinse dental plaque produced 36% less lactate, 36% less acetate and 44% less propionate than after the negative control rinse. The dental plaque also exhibited a pH 0.42 unit higher after EO rinse than after the negative control rinse. These results were not affected by the addition of 100 mg\/kg fluoride to the EO mouthrinse. From these results we concluded that this EO antiseptic mouthrinse, with or without fluoride ion, is effective in reduction of plaque acidogenicity after a sucrose challenge.<\/jats:p>","DOI":"10.1159\/000080583","type":"journal-article","created":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T13:50:20Z","timestamp":1099317020000},"page":"537-541","source":"Crossref","is-referenced-by-count":10,"title":["Effect of an Essential Oil Mouthrinse, with and without Fluoride, on Plaque Metabolic Acid Production and pH after a Sucrose Challenge"],"prefix":"10.1159","volume":"38","author":[{"given":"J.Z.","family":"Zhang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.S.","family":"Harper","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.L.","family":"Vogel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Schumacher","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2004,10,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-051x.2000.027003157.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000262066"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0003-9969%2897%2900044-7"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-051X.1996.tb00604.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177%2F10454411970080030301"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0003-9969%2890%2990071-H"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-051X.1990.tb01108.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-051x.2000.027004256.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1902%2Fjop.2001.72.8.1059"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0003-9969%2898%2900125-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345980770031101"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345000790041501"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159%2F000057590"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/80583","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/80583","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:36:49Z","timestamp":1745465809000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000080583"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":13,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2004,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000080583","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"value":"0008-6568","type":"print"},{"value":"1421-976X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004]]}}}