{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T06:26:58Z","timestamp":1777444018189,"version":"3.51.4"},"reference-count":9,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2004,1,1]],"date-time":"2004-01-01T00:00:00Z","timestamp":1072915200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2004]]},"abstract":"<jats:p>This study was performed to quantify the volumetric impact of extracranial arteriosclerotic lesions. We investigated patients with different degrees of carotid stenosis as defined by conventional velocity-based duplex criteria and different patterns of collateralization. We studied the volume flow rate (color duplex M-mode device) in 37 patients with symmetrical internal carotid artery (ICA) plaques (&lt;50% stenosis) and compared these data to 43 patients with a unilateral 50\u201374% stenosis, 75\u201399% stenosis (n = 73) and occlusion of the ICA (n = 37). A 75\u201399% stenosis caused an ipsilateral flow reduction of 36% with a wide interindividual variability, and an occlusion of 51%. Collateralization via the ophthalmic artery only caused a nonsignificant ipsilateral volume flow increase, whereas the contralateral volume flow was significantly higher in patients with a patent anterior communicating artery. The increase was more pronounced in patients with an occluded vessel. Our data demonstrate a wide diversity of the hemodynamic impact of carotid stenosis as defined by \u2018classical\u2019 Doppler criteria. Collateral flow reflects a dynamic quantitative process.<\/jats:p>","DOI":"10.1159\/000080698","type":"journal-article","created":{"date-parts":[[2004,9,8]],"date-time":"2004-09-08T08:46:05Z","timestamp":1094633165000},"page":"312-317","source":"Crossref","is-referenced-by-count":11,"title":["Volume Flow Rate Evaluation in Patients with Obstructive Arteriosclerotic Disease"],"prefix":"10.1159","volume":"18","author":[{"given":"Claudia","family":"Doberenz","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Paulus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carl D.","family":"Reimers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B. Martin","family":"Eicke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2004,12,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2007-1011629"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1067%2Fmva.1986.avs0030846"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1067%2Fmva.1987.avs0050594"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000107839"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-5629%2896%2900224-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0301-5629%2895%2900024-L"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1067%2Fmva.1993.42888"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0741-5214%2895%2970228-8"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2F0140-6736%2891%2992916-P"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/80698","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/80698","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:37:25Z","timestamp":1745465845000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000080698"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004]]},"references-count":9,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2004,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000080698","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"value":"1015-9770","type":"print"},{"value":"1421-9786","type":"electronic"}],"subject":[],"published":{"date-parts":[[2004]]}}}