{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:10:57Z","timestamp":1745554257759,"version":"3.40.4"},"reference-count":47,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2004,12,23]],"date-time":"2004-12-23T00:00:00Z","timestamp":1103760000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2004,12,23]],"date-time":"2004-12-23T00:00:00Z","timestamp":1103760000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gyn\u00e4kol Geburtshilfliche Rundsch"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>Die Antibiotikaresistenz von Mikroorganismen, die f\u00fcr Infektionen des Urogenitaltraktes verantwortlich sind, ist ein klinisch relevantes Problem in der Gyn\u00e4kologie und Geburtshilfe. Gleichzeitig wird die Resistenzpr\u00fcfung aufgrund methodologischer Schwierigkeiten sehr selten eingesetzt, so dass genaue Angaben \u00fcber die Epidemiologie der Antibiotikaresistenz bei den meisten Erregern fehlen. In verschiedenen Regionen scheint die Antibiotikaresistenz von &lt;i&gt;Trichomonas vaginalis&lt;\/i&gt; und &lt;i&gt;Gardnerella vaginalis&lt;\/i&gt; (Metronidazol), &lt;i&gt;Streptococcus agalactiae &lt;\/i&gt;(Makrolide, Clindamycin), &lt;i&gt;Mycoplasma hominis&lt;\/i&gt; (Tetracycline, bei vorbestehender intrinsischer Resistenz gegen Makrolide) zuzunehmen. Zus\u00e4tzlich wurden Einzelf\u00e4lle klinischer Infektionen durch multiresistente &lt;i&gt;Chlamydia trachomatis&lt;\/i&gt; berichtet. Das Vorliegen einer Antibiotikaresistenz sollte deshalb bei unbefriedigendem klinischem Verlauf in Betracht gezogen werden. Angesichts der zunehmenden Resistenzproblematik und der zum Teil grossen Wissensl\u00fccken sollten die Forschungsanstrengungen auf dem Gebiet der Antibiotikaresistenz bei gyn\u00e4kologischen Infektionen intensiviert werden.<\/jats:p>","DOI":"10.1159\/000081713","type":"journal-article","created":{"date-parts":[[2005,1,20]],"date-time":"2005-01-20T08:44:42Z","timestamp":1106210682000},"page":"19-27","source":"Crossref","is-referenced-by-count":1,"title":["Klinische Bedeutung der Antibiotikaresistenz in Gyn\u00e4kologie und 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