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Die Sentinel-Lymphonodektomie hat sich als neuer operativer Standard etabliert und sollte allen Patientinnen mit unizentrischen Tumoren unter 3 cm Durchmesser angeboten werden. Die offenen Fragen betreffen vor allem den Injektionsort der Markersubstanz, die Bedeutung des Auffindens und Entfernens extra-axill\u00e4rer Lymphknoten und die Anwendbarkeit der Methode bei multizentrischem Tumor, nach neoadjuvanter Chemotherapie, vorausgegangener Brustbiopsie, beim DCIS und bei Tumoren von mehr als 3 cm Gr\u00f6sse. Auch das Vorgehen nach Auffinden von Mikrometastasen ist noch Gegenstand wissenschaftlicher Studien.<\/jats:p>","DOI":"10.1159\/000081714","type":"journal-article","created":{"date-parts":[[2005,1,20]],"date-time":"2005-01-20T08:44:42Z","timestamp":1106210682000},"page":"28-38","source":"Crossref","is-referenced-by-count":1,"title":["Sentinel-Lymphonodektomie \u2013 Der neue operative Standard f\u00fcr die Evaluation der Axilla: Ein \u00dcberblick"],"prefix":"10.1159","volume":"45","author":[{"given":"Christoph 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