{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T10:43:28Z","timestamp":1790073808492,"version":"4.0.1"},"reference-count":12,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To study the etiology and outcome of non-immune hydrops fetalis in southern Thailand. &lt;i&gt;Methods:&lt;\/i&gt; The medical records and videotape recordings of all pregnant women diagnosed with non-immune fetal hydrops, from January 1993 to December 2002 were reviewed. &lt;i&gt;Results:&lt;\/i&gt; Non-immune hydrops fetalis was documented in 71 cases. The causes of fetal hydrops were identified in 87.3%. Homozygous \u03b1-thalassemia-1 dominated as the cause of non-immune fetal hydrops (28.2%), followed by structural abnormalities (15.5%) and infection (12.7%). The underlying etiology remained unknown in 9 cases (12.7%). The overall survival rate of non-immune hydrops fetalis cases was 4.2%. Spontaneous regression occurred in 2 cases. Two cases were lost to follow up after initial evaluation. Termination of pregnancy was performed in 47 cases. There were 12 dead fetuses in utero, 2 stillbirths, 5 early neonatal deaths and only 3 cases survived. &lt;i&gt;Conclusions:&lt;\/i&gt; Homozygous \u03b1-thalassemia-1 is the most common cause of non-immune hydrops fetalis in southern Thailand, and the overall prognosis of non-immune hydrops fetalis is poor. We suggest that an effective thalassemia-screening program for prevention and control of homozygous \u03b1-thalassemia-1 be established in all areas where the \u03b1-thalassemia-1 gene is prevalent.<\/jats:p>","DOI":"10.1159\/000082997","type":"journal-article","created":{"date-parts":[[2005,1,20]],"date-time":"2005-01-20T08:44:42Z","timestamp":1106210682000},"page":"134-137","source":"Crossref","is-referenced-by-count":38,"title":["Etiology and Outcome of Non-Immune Hydrops fetalis in Southern Thailand"],"prefix":"10.1159","volume":"59","author":[{"given":"Chitkasaem","family":"Suwanrath-Kengpol","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ounjai","family":"Kor-anantakul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thitima","family":"Suntharasaj","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roengsak","family":"Leetanaporn","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,4,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320340313"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080%2F714904328"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0412.2000.079001015.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs100249900146"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0029-7844%2894%2900444-I"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.1996.08030196.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291097-0096%28199602%2924%3A2%3C73%3A%3AAID-JCU4%3E3.0.CO%3B2-H"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0412.2001.080008726.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0029-7844%2897%2900290-1"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0301-2115%2800%2900241-4"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0029-7844%2801%2901455-7"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159%2F000264214"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/82997","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/82997","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:28:28Z","timestamp":1745465308000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000082997"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000082997","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}