{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T18:37:48Z","timestamp":1789756668011,"version":"4.0.1"},"reference-count":29,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Histological structures of the skin are often irregular in size and shape. Euclidean geometry and fractal analysis are complementary for assessing distinct aspects of their dimensions. &lt;i&gt;Objective:&lt;\/i&gt; To determine and compare the variations in shape of the dermo-epidermal junction and the size of the superficial vessels in psoriatic lesions. &lt;i&gt;Method:&lt;\/i&gt; The relative microvasculature area and the fractal dimension D of the dermo-epidermal interface were measured inside and outside growth-stunted guttate lesions (n = 22) and expanding plaques (n\u00a0= 37) in psoriasis of the trunk. &lt;i&gt;Results:&lt;\/i&gt; The median D values of the dermo-epidermal interface were significantly larger (p &lt; 0.01) in psoriatic plaques (D = 1.15) than in guttate lesions (D = 1.08), and these D values on lesional skin were significantly larger (p &lt; 0.01) than in the uninvolved skin (D = 1.03). The microvasculature was significantly (p &lt; 0.01) more developed in lesional (plaque: 13%, guttate: 8.20%) than in uninvolved skin (3.60 and 3.85%). No correlations were found between the relative microvasculature areas and the D values of the dermo-epidermal interface, both in the uninvolved and lesional skins of each psoriatic type. &lt;i&gt;Conclusion:&lt;\/i&gt; The absence of a relationship between modulations of the dermo-epidermal junction and vascular hyperplasia, both in expanding and stable psoriasis lesions, suggests that these events are regulated by different mechanisms and do not depend on each other.<\/jats:p>","DOI":"10.1159\/000083508","type":"journal-article","created":{"date-parts":[[2005,3,21]],"date-time":"2005-03-21T15:12:21Z","timestamp":1111417941000},"page":"189-193","source":"Crossref","is-referenced-by-count":10,"title":["Vascularity and Fractal Dimension of the Dermo-Epidermal Interface in Guttate and Plaque-Type Psoriasis"],"prefix":"10.1159","volume":"210","author":[{"given":"Isabelle","family":"Uhoda","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G\u00e9rald E.","family":"Pi\u00e9rard","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudine","family":"Pi\u00e9rard-Franchimont","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jorge 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