{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:08Z","timestamp":1787017868046,"version":"build-2736575974"},"reference-count":21,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2005]]},"abstract":"<i>Background:<\/i> Perinatal asphyxia constitutes a significant problem influencing neonatal mortality and morbidity. <i>Objectives:<\/i> The aim of the present work was to provide evidence of the usefulness of cardiac troponin T (cTnT) and echocardiographic investigations in the diagnosis of heart damage in full-term infants after intrauterine hypoxia. <i>Material and Methods:<\/i> The subjects were 39 asphyxiated and 44 term infants without fetal anoxia. Quantitative determinations of cTnT were performed between 12 and 24 h of life. Two-dimensional Doppler and color Doppler studies were performed at the bedside. We evaluated fractional shortening (FS), cardiac output (CO), cardiac index (CI), tricuspid (TI) and mitral (MI) insufficiency. <i>Results:<\/i> Asphyxiated infants presented increased cTnT (mean 0.141 \u00b1 0.226 vs. 0.087 \u00b1 0.111ng\/ml; p < 0.01) and TI (38.5 vs. 11.4% of population; p < 0.05) compared to healthy infants. CO, CI and FS remained in the same range. <i>Conclusions:<\/i> We found cTnT to be the most useful among accessible diagnostic tools used in post-hypoxic heart damage in neonates. The data from our relatively small population study suggest a cTnT value of >0.1 ng\/ml as a reliable marker of myocardial injury in neonates. Further study should be performed to generate a receiver-operator characteristic curve to discover what the cut-off level should be.<\/jats:p>","DOI":"10.1159\/000084067","type":"journal-article","created":{"date-parts":[[2005,3,3]],"date-time":"2005-03-03T06:09:56Z","timestamp":1109830196000},"page":"19-23","source":"Crossref","is-referenced-by-count":47,"title":["Usefulness of Cardiac Troponin T and Echocardiography in the Diagnosis of Hypoxic Myocardial Injury of Full-Term Neonates"],"prefix":"10.1159","volume":"88","author":[{"given":"Marta","family":"Szymankiewicz","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marzena","family":"Matuszczak-Wleklak","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joan E.","family":"Hodgman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janusz","family":"Gadzinowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,7,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00045415-200111000-00006"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1258%2F0004563011901109"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2FBF02887676"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0167-5273%2802%2900144-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-8703%2887%2990717-4"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.99.6.851"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2F1098-2779%28200102%297%3A1%3C56%3A%3AAID-MRDD1008%3E3.0.CO%3B2-A"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0929-693X%2800%2900311-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00431-003-1321-9"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136%2Fheart.89.11.1303"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2F0009-9120%2894%2990021-3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9343%2803%2900348-6"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080%2F08035250310007637"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000013973"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159%2F000013999"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1136%2Ffn.84.1.F34"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1080%2F08035250121110"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2000.106753"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159%2F000014281"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159%2F000014089"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9378%2899%2970119-5"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84067","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84067","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:39:59Z","timestamp":1745451599000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000084067"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2005,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000084067","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}