{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,1,18]],"date-time":"2024-01-18T13:45:48Z","timestamp":1705585548090},"reference-count":23,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pancreatology"],"published-print":{"date-parts":[[2005,1]]},"DOI":"10.1159\/000084495","type":"journal-article","created":{"date-parts":[[2005,3,18]],"date-time":"2005-03-18T08:06:18Z","timestamp":1111133178000},"page":"92-96","source":"Crossref","is-referenced-by-count":5,"title":["Relapsing pancreatitis due to a novel compound heterozygosity in the CFTR gene involving the second most common mutation in central and eastern europe [CFTRdele2,3(21 kb)]"],"prefix":"10.1016","volume":"5","author":[{"given":"Georg","family":"Lamprecht","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ulrike A.","family":"Mau","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Kort\u00fcm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Armin","family":"Raible","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Stern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olaf","family":"Rie\u00df","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Gregor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Keim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1159\/000084495_bib1","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1038\/ng1096-141","article-title":"Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene","volume":"14","author":"Whitcomb","year":"1996","journal-title":"Nat Genet"},{"key":"10.1159\/000084495_bib2","doi-asserted-by":"crossref","first-page":"213","DOI":"10.1038\/76088","article-title":"Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis","volume":"25","author":"Witt","year":"2000","journal-title":"Nat Genet"},{"key":"10.1159\/000084495_bib3","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1053\/gast.2000.18017","article-title":"SPINK1\/PSTI polymorphisms act as disease modifiers in familial and idiopathic chronic pancreatitis","volume":"119","author":"Pfutzer","year":"2000","journal-title":"Gastroenterology"},{"key":"10.1159\/000084495_bib4","doi-asserted-by":"crossref","first-page":"687","DOI":"10.1136\/gut.50.5.687","article-title":"Mutations in serine protease inhibitor Kazal type 1 are strongly associated with chronic pancreatitis","volume":"50","author":"Drenth","year":"2002","journal-title":"Gut"},{"key":"10.1159\/000084495_bib5","doi-asserted-by":"crossref","first-page":"621","DOI":"10.1016\/S0025-7125(05)70245-5","article-title":"Cystic fibrosis mutations and genetic predisposition to idiopathic chronic pancreatitis","volume":"84","author":"Cohn","year":"2000","journal-title":"Med Clins N Am"},{"key":"10.1159\/000084495_bib6","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1146\/annurev.ge.29.120195.004021","article-title":"Cystic fibrosis: genotypic and phenotypic variations","volume":"29","author":"Zielenski","year":"1995","journal-title":"Annu Rev Genet"},{"key":"10.1159\/000084495_bib7","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1053\/gast.2001.22586","article-title":"Chronic pancreatitis: Diagnosis, classification, and new genetic developments","volume":"120","author":"Etemad","year":"2001","journal-title":"Gastroenterology"},{"key":"10.1159\/000084495_bib8","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1186\/1471-230X-3-34","article-title":"A novel mutation of the calcium sensing receptor gene is associated with chronic pancreatitis in a family with heterozygous SPINK1 mutations","volume":"3","author":"Felderbauer","year":"2003","journal-title":"BMC Gastroenterol"},{"key":"10.1159\/000084495_bib9","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1152\/physrev.1999.79.1.S145","article-title":"CFTR is a conductance regulator as well as a chloride channel","volume":"79","author":"Schwiebert","year":"1999","journal-title":"Physiol Rev"},{"key":"10.1159\/000084495_bib10","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1097\/00006676-199601000-00001","article-title":"Pancreatic dysfunction in cystic fibrosis occurs as a result of impairments in luminal pH, apical trafficking of zymogen granule membranes, and solubilization of secretory enzymes","volume":"12","author":"Scheele","year":"1996","journal-title":"Pancreas"},{"key":"10.1159\/000084495_bib11","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s004390000246","article-title":"Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: A cystic fibrosis mutation of Slavic origin common in Central and East Europe","volume":"106","author":"Dork","year":"2000","journal-title":"Hum Genet"},{"key":"10.1159\/000084495_bib12","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1038\/ng1193-274","article-title":"A mutation in CFTR produces different phenotypes depending on chromosomal background","volume":"5","author":"Kiesewetter","year":"1993","journal-title":"Nat Genet"},{"key":"10.1159\/000084495_bib13","doi-asserted-by":"crossref","first-page":"400","DOI":"10.1034\/j.1399-0004.1999.560509.x","article-title":"Polyvariant mutant CFTR genes in patients with chronic pancreatitis","volume":"56","author":"Arduino","year":"1999","journal-title":"Clin Genet"},{"key":"10.1159\/000084495_bib14","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1038\/sj.ejhg.5200786","article-title":"Determination of the relative contribution of three genes-the cystic fibrosis transmembrane conductance regulator gene, the cationic trypsinogen gene, and the pancreatic secretory trypsin inhibitor gene-to the etiology of idiopathic chronic pancreatitis","volume":"10","author":"Audrezet","year":"2002","journal-title":"Eur J Hum Genet"},{"key":"10.1159\/000084495_bib15","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJM199809033391002","article-title":"Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis","volume":"339","author":"Cohn","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1159\/000084495_bib16","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1056\/NEJM199809033391001","article-title":"Mutations of the cystic fibrosis gene in patients with chronic pancreatitis","volume":"339","author":"Sharer","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1159\/000084495_bib17","doi-asserted-by":"crossref","first-page":"7","DOI":"10.1007\/BF00218824","article-title":"Congenital bilateral absence of the vas deferens (CBAVD) and cystic fibrosis transmembrane regulator (CFTR): Correlation between genotype and phenotype","volume":"97","author":"Dumur","year":"1996","journal-title":"Hum Genet"},{"key":"10.1159\/000084495_bib18","first-page":"907","article-title":"Pancr\u00e9atite chronique non alcoolique: la mutation delta F508 du g\u00e8ne CFTR pourraitelle \u00eatre consider\u00e9e comme un facteur de risque?","volume":"18","author":"Aygalenq","year":"1994","journal-title":"Gastroenterol Clin Biol"},{"key":"10.1159\/000084495_bib19","doi-asserted-by":"crossref","first-page":"645","DOI":"10.1056\/NEJM199809033391001","article-title":"Mutations of the cystic fibrosis gene in patients with chronic pancreatitis","volume":"339","author":"Sharer","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1159\/000084495_bib20","doi-asserted-by":"crossref","first-page":"653","DOI":"10.1056\/NEJM199809033391002","article-title":"Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis","volume":"339","author":"Cohn","year":"1998","journal-title":"N Engl J Med"},{"key":"10.1159\/000084495_bib21","doi-asserted-by":"crossref","first-page":"2657","DOI":"10.1111\/j.1572-0241.2001.04047.x","article-title":"Mutations of the cystic fibrosis gene in patients with chronic pancreatitis","volume":"96","author":"Truninger","year":"2001","journal-title":"Am J Gastroenterol"},{"key":"10.1159\/000084495_bib22","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1159\/000084495","article-title":"Relapsing pancreatitis due to a novel compound heterozygosity in the CFTR gene involving the second most mutation in central and eastern Europe [CFTRdele2,3(21 kb)]","volume":"5","author":"Lamprecht","year":"2005","journal-title":"Pancreatology"},{"key":"10.1159\/000084495_bib23","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1007\/s004390000246","article-title":"Characterization of a novel 21-kb deletion, CFTRdele2,3(21 kb), in the CFTR gene: A cystic fibrosis mutation of Slavic origin common in Central and East. Europe","volume":"106","author":"Dork","year":"2000","journal-title":"Hum Genet"}],"container-title":["Pancreatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390305800432?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1424390305800432?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,4]],"date-time":"2019-02-04T10:52:28Z","timestamp":1549277548000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1424390305800432"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,1]]},"references-count":23,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2005,1]]}},"alternative-id":["S1424390305800432"],"URL":"https:\/\/doi.org\/10.1159\/000084495","relation":{},"ISSN":["1424-3903"],"issn-type":[{"value":"1424-3903","type":"print"}],"subject":[],"published":{"date-parts":[[2005,1]]}}}