{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T11:16:12Z","timestamp":1788520572037,"version":"build-2803163510"},"reference-count":15,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Digestion"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Aim:&lt;\/i&gt; Investigation of the prevalence of respiratory symptoms and diseases associated with gastroesophageal reflux disease (GERD). &lt;i&gt;Patients and Methods:&lt;\/i&gt; 299 subjects with GERD were submitted to upper gastrointestinal endoscopy and 24-hour esophageal pH monitoring and a symptom analysis. &lt;i&gt;Results:&lt;\/i&gt; Chronic respiratory symptoms or diseases were present in 18% (56\/299). Chronic cough was observed in 42\/56 patients, while typical reflux symptoms such as heartburn and acid regurgitation were observed in 30\/56 and 24\/56 cases, respectively. The prevalence of airway diseases was chronic bronchitis 12\/56, asthma 10\/56, recurrent pneumonia 10\/56, chronic sinusitis 7\/56 and chronic laryngitis 1\/56. In patients with respiratory complications pathologic acid reflux was established in 29\/51 cases on the basis of the DeMeester score, while 17\/51 had pathologic postprandial, nocturnal or diurnal reflux events. Upper gastrointestinal endoscopy revealed a normal esophageal mucosa in 6\/56, Savary-Miller stage I esophagitis in 23\/56, stage II in 15\/56, stage III in 5\/56 and stage IV in 6\/56 patients. &lt;i&gt;Conclusions:&lt;\/i&gt; These investigations have demonstrated an abnormal 24-hour pH score in about half of the patients with GERD-associated respiratory complications, and indicated that short reflux events are characteristic of the reflux activity in one third of this population.<\/jats:p>","DOI":"10.1159\/000084524","type":"journal-article","created":{"date-parts":[[2005,3,18]],"date-time":"2005-03-18T13:06:18Z","timestamp":1111151178000},"page":"92-96","source":"Crossref","is-referenced-by-count":16,"title":["Prevalence of Respiratory Symptoms and Diseases Associated with Gastroesophageal Reflux Disease"],"prefix":"10.1159","volume":"71","author":[{"given":"Rich\u00e1rd","family":"R\u00f3ka","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andr\u00e1s","family":"Roszt\u00f3czy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ferenc","family":"Izb\u00e9ki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zolt\u00e1n","family":"Taybani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ildik\u00f3","family":"Kiss","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00e1nos","family":"Lonovics","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tibor","family":"Wittmann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,4,20]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9343%2897%2900329-X"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.106.6.1793"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.115.3.654"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.116.2.279"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5085%2897%2970168-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.121.1.158"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9343%2801%2900817-8"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS1091-255X%2898%2980073-5"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007%2FBF01296157"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136%2Fgut.33.7.872"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.109.2.316"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00042737-200312000-00013"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2036.2003.01606.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9270%2800%2901071-6"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.104.5.1511"}],"container-title":["Digestion"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84524","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84524","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:43:06Z","timestamp":1745466186000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000084524"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":15,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000084524","archive":["Portico"],"relation":{},"ISSN":["0012-2823","1421-9867"],"issn-type":[{"value":"0012-2823","type":"print"},{"value":"1421-9867","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}