{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:10:48Z","timestamp":1745554248259,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2005]]},"abstract":"<i>Objective:<\/i> This study was planned to investigate the efficacy of either <sup>99m<\/sup>Tc-sestamibi scan or ultrasonography in predicting the operative treatment in patients with primary hyperparathyroidism (PHPT). <i>Subjects and Method:<\/i> Thirty patients (25 female, 5 male; mean age: 53 years) being operated for symptomatic primary PHPT were included in this study. Ultrasonography was used in 29 patients while <sup>99m<\/sup>Tc-sestamibi scintigraphy was done in 28 patients to localize the hyperfunctioning gland(s). Standard bilateral neck exploration was done in 6 patients. Although unilateral intervention had been planned for 24 patients, bilateral intervention was performed in 9 of them. <i>Results:<\/i> Sensitivity of <sup>99m<\/sup>Tc-sestamibi was 81%, while that of ultrasonography was 42%. <sup>99m<\/sup>Tc-sestamibi localization method led to misleading results in 10\/28 (35.7%) patients. False-positive localization and accompanying thyroid pathologies played an important role in determining transition from unilateral to bilateral intervention. <i>Conclusion: <\/i>Our findings indicate that bilateral intervention remains a successful management option without prior localization in patients with PHPT especially in an endemic goiter region.<\/jats:p>","DOI":"10.1159\/000084639","type":"journal-article","created":{"date-parts":[[2005,4,29]],"date-time":"2005-04-29T13:02:27Z","timestamp":1114779747000},"page":"194-198","source":"Crossref","is-referenced-by-count":0,"title":["Surgical Management Strategies in Patients with Primary Hyperparathyroidism: Which Technique in Which Patients?"],"prefix":"10.1159","volume":"14","author":[{"given":"Ayhan","family":"Koyuncu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatice Sebila","family":"D\u00f6kmeta\u015f","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cengiz","family":"Ayd\u0131n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mustafa","family":"Turan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taner","family":"Erselcan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sel\u00e7uk","family":"S\u00f6zeri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Metin","family":"\u015een","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,4,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198001243020402"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0011-3840%2897%2980008-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800690503"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2F00000658-200211000-00001"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2002-021095"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0889-8529%2805%2970146-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00000658-199509000-00017"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199910213411701"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1007%2Fs007740170007"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs004230050252"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0753-3322%2802%2900260-3"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2F0011-3840%2885%2990019-X"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2265.2002.01581.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00006231-200302000-00002"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1001%2Farchsurg.137.8.896"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS1072-7515%2802%2901897-5"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84639","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84639","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:43:52Z","timestamp":1745466232000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000084639"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":16,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000084639","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2005]]}}}