{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T19:25:26Z","timestamp":1790623526840,"version":"4.1.0"},"reference-count":20,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; An association of mental stress with atopic dermatitis is widely accepted. However, no long-term evaluation of psychophysiological reactivity over the course of disease has yet been performed. &lt;i&gt;Objective:&lt;\/i&gt; We examined whether atopic dermatitis patients have an increased psychophysiological reactivity compared to healthy controls and in between acute and disease-free phases, and whether they differ in psychological state and trait variables. &lt;i&gt;Methods:&lt;\/i&gt; Fifteen patients with atopic dermatitis underwent a stress test during acute exacerbation and after symptom improvement and were compared to matched controls. &lt;i&gt;Results:&lt;\/i&gt; Psychophysiological responsesto stress were not stronger in the patient group than in the controls. Nevertheless, the patients had a higher heart rate and lower vagal activity throughout the resting and stress phases at both examination times. The patients showed significantly higher anxiety, depression and emotional excitability, and self-ratings of inactivity clearly distinguished acute phases from remission. &lt;i&gt;Conclusion:&lt;\/i&gt; There is an increased vegetative excitability level in patients with atopic dermatitis, which cannot be attributed solely to increased disease activity.<\/jats:p>","DOI":"10.1159\/000084752","type":"journal-article","created":{"date-parts":[[2005,5,27]],"date-time":"2005-05-27T10:28:02Z","timestamp":1117189682000},"page":"286-293","source":"Crossref","is-referenced-by-count":40,"title":["Psychophysiological Reactivity under Mental Stress in Atopic Dermatitis"],"prefix":"10.1159","volume":"210","author":[{"given":"Kristina","family":"Seiffert","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edwin","family":"Hilbert","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hartmut","family":"Schaechinger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christos C.","family":"Zouboulis","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hans-Christian","family":"Deter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2894%2970213-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000056219"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-4362.1993.tb04021.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000068463"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS1054-3589%2808%2960818-2"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2882%2990008-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1995.tb08619.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2894%2992473-2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2001.109815"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2001.111850"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000247232"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111%2F1523-1747.ep12371746"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1600-0625.2002.110102.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2F0022-3999%2885%2990027-3"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2F0022-3999%2892%2990075-D"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159%2F000247298"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00004872-199715080-00006"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.6166045"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1037%2Fh0037085"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1159%2F000051699"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84752","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84752","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:45:39Z","timestamp":1745466339000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000084752"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":20,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2005,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000084752","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}