{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:10:56Z","timestamp":1745554256358,"version":"3.40.4"},"reference-count":12,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Protein-calorie malnutrition is present in 30\u201350% of dialysis patients. The lack of biocompatibility of the dialysis membrane, which results in low-grade inflammation, could be responsible for this malnutrition. We investigated whether protein-energy malnutrition could be partly due to incompatibility of the dialyzer during the dialysis session. &lt;i&gt;Methods:&lt;\/i&gt; Five patients were dialyzed during 2 periods of 3 weeks (cross-over) with either a single-use low-flux polysulfone or cellulose triacetate (biocompatible) or a single-use cuprophan (bio-incompatible) membrane. As a measure of whole body protein metabolism, a primed constant infusion of &lt;i&gt;L&lt;\/i&gt;-[1-&lt;sup&gt;13&lt;\/sup&gt;C]-valine was used during a 4-hour dialysis session. &lt;i&gt;Results:&lt;\/i&gt; Cuprophan was a more powerful activator of the complement system than other membranes. Protein metabolism parameters during both study protocols were not different and resulted in the same protein balance during polysulfone\/cellulose triacetate (\u201315 \u00b1 3) and cuprophan (\u201313 \u00b1 2 \u00b5mol\/kg\/h) dialysis. &lt;i&gt;Conclusion:&lt;\/i&gt; In stable hemodialysis patients with no apparent complications, protein metabolism during dialysis is not affected by the compatibility of the dialysis membrane.<\/jats:p>","DOI":"10.1159\/000084891","type":"journal-article","created":{"date-parts":[[2005,4,4]],"date-time":"2005-04-04T14:58:20Z","timestamp":1112626700000},"page":"211-218","source":"Crossref","is-referenced-by-count":3,"title":["Membrane Biocompatibility Does Not Affect Whole Body Protein Metabolism during Dialysis"],"prefix":"10.1159","volume":"23","author":[{"given":"Jorden M.","family":"Veeneman","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hermi A.","family":"Kingma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Frans","family":"Stellaard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul E.","family":"de Jong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk-Jan","family":"Reijngoud","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roel M.","family":"Huisman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,5,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1523-1755.2000.00135.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1172%2FJCI116477"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1990.230"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1994.337"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1996.78"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1525-139X.2001.00041.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0009-9120%2880%2991040-1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0026-0495%2882%2990160-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2003.10.020"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2F13.1.113"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038%2Fki.1994.339"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.2002.30545"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84891","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/84891","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:46:31Z","timestamp":1745466391000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000084891"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":12,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2005,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000084891","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"type":"print","value":"0253-5068"},{"type":"electronic","value":"1421-9735"}],"subject":[],"published":{"date-parts":[[2005]]}}}