{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,1]],"date-time":"2025-10-01T16:34:27Z","timestamp":1759336467458,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; A fetal ultrasonographic (US) finding of mild ventriculomegaly (MVM) is not uncommon, but its prognostic significance is not clearly defined. &lt;i&gt;Objective:&lt;\/i&gt; To evaluate the clinical and US characteristics and outcome of fetuses with mild dilatation of the cerebral lateral ventricles. &lt;i&gt;Patients and Methods:&lt;\/i&gt; We reviewed the medical records of 34 consecutive fetuses with US evidence of MVM (atrial width of the lateral ventricles = 10\u201315 mm) at 18\u201335 weeks of gestation. &lt;i&gt;Results:&lt;\/i&gt; Of the 34 fetuses with MVM, 7 underwent karyotype examination and were normal. In 4 of the 34 fetuses the pregnancy was terminated (at autopsy: 1 was normal, 2 had hydrocephalus and for 1 the parents refused autopsy). Eight fetuses that were delivered had congenital malformations; 3 of them died during the early neonatal period. In 6 of the 8 fetuses with malformations, karyotypes were available and 3 had chromosomal aberrations (trisomy 18, 45XO, and triploidy 69XXX). Spontaneous in utero resolution of the MVM occurred in 10\/30 (33.3%) of the cases. Of the 26 infants that remained in follow-up, 16 (61.1%) were normal at 1 month and at 2 years of age. &lt;i&gt;Conclusions:&lt;\/i&gt; Our data confirm those of previous reports as to the characteristics and outcome of MVM. In the setting of mild fetal ventriculomegaly with a normal karyotype and an absence of malformations, the outcome appears to be favorable.<\/jats:p>","DOI":"10.1159\/000085086","type":"journal-article","created":{"date-parts":[[2005,6,24]],"date-time":"2005-06-24T08:57:06Z","timestamp":1119603426000},"page":"281-284","source":"Crossref","is-referenced-by-count":26,"title":["Mild Cerebral Ventriculomegaly in Fetuses: Characteristics and Outcome"],"prefix":"10.1159","volume":"20","author":[{"given":"Israel","family":"Goldstein","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua A.","family":"Copel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Imad R.","family":"Makhoul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,6,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.138"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1067%2Fmob.2002.127146"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.1993.03020089.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2007-999452"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291520-6661%28199707%2F08%296%3A4%3C241%3A%3AAID-MFM11%3E3.0.CO%3B2-H"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291097-0223%28199806%2918%3A6%3C557%3A%3AAID-PD303%3E3.3.CO%3B2-V"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.1998.12010023.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9378%2898%2980003-3"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1469-0705.1999.14050320.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.261.12.1785"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000263529"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85086","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85086","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:01Z","timestamp":1745466541000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000085086"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":11,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2005,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000085086","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"type":"print","value":"1015-3837"},{"type":"electronic","value":"1421-9964"}],"subject":[],"published":{"date-parts":[[2005]]}}}