{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:11:03Z","timestamp":1745554263272,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Intervirology"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>We studied the sensitivity of several human cancer cell strains (HeLa, HT1080, SPC-A1, and ACHN) and normal cell strains (MRC-5 and Wish) to mumps virus (MuV) S&lt;sub&gt;79&lt;\/sub&gt;, a live attenuated vaccine strain. These cells exhibited a differential sensitivity to infection with MuV, and the susceptible sequences were ACHN &gt; HeLa &gt; HT1080 &gt; SPC-A1 &gt; Wish &gt; MRC-5. In experiments in vivo, nude mice with HT1080 fibrosarcoma xenografts were randomly divided into three groups for intratumoral treatment with MuVS&lt;sub&gt;79&lt;\/sub&gt;, UV-inactivated MuVS&lt;sub&gt;79&lt;\/sub&gt;, and PBS. At 10&lt;sup&gt;7&lt;\/sup&gt; PFU, live MuVS&lt;sub&gt;79&lt;\/sub&gt; injection caused in 7 of 9 mice complete regression by day 15 while rapid tumor growth occurred in all 9 mice treated with PBS. Rapid tumor progression also occurred in all 8 mice treated with UV-inactivated virus; however, tumor growth was delayed in the logarithmic phase relative to the PBS-treated tumors.<\/jats:p>","DOI":"10.1159\/000085097","type":"journal-article","created":{"date-parts":[[2005,6,13]],"date-time":"2005-06-13T12:10:45Z","timestamp":1118664645000},"page":"292-296","source":"Crossref","is-referenced-by-count":5,"title":["Selective Cytolysis of Tumor Cells by Mumps Virus S&lt;sub&gt;79&lt;\/sub&gt;"],"prefix":"10.1159","volume":"48","author":[{"given":"Yin-Fang","family":"Yan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiao","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jian-Guo","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Yuan","family":"Dong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,6,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.282.5392.1332"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1128%2FJVI.75.5.2087-2096.2001"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1038%2Fnm0995-938"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%28197412%2934%3A6%3C1907%3A%3AAID-CNCR2820340609%3E3.0.CO%3B2-4"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0166-3542%2892%2990091-I"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1432-1033.1989.tb14719.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3468%2805%2980302-1"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1073%2Fpnas.68.4.836"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0960-9822%2806%2900297-1"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.277.5327.815"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0165-2427%2802%2900012-0"}],"container-title":["Intervirology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85097","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85097","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:07Z","timestamp":1745466547000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000085097"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":11,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2005,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000085097","archive":["Portico"],"relation":{},"ISSN":["0300-5526","1423-0100"],"issn-type":[{"type":"print","value":"0300-5526"},{"type":"electronic","value":"1423-0100"}],"subject":[],"published":{"date-parts":[[2005]]}}}