{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T22:14:07Z","timestamp":1761862447164,"version":"3.40.4"},"reference-count":23,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Int Arch Allergy Immunol"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; There is some evidence that specific immunotherapy may induce de novo sensitization to proteins contained in the allergen extract. This raises the possibility that the novel sensitization to cross-reacting allergens may cause food allergies. &lt;i&gt;Objective:&lt;\/i&gt; The aim of this study was to assess whether injection of mite-specific immunotherapy (SIT) may induce sensitization to shrimp tropomyosin. &lt;i&gt;Methods:&lt;\/i&gt; Seventy mite-allergic subjects who did not show any shrimp sensitization at baseline were followed up for at least 3 years. Thirty-one of them underwent a 3-year SIT course, 39 served as controls. At the follow-up visit, SPTs with both fresh shrimp and commercial extract were performed, and patients underwent an open oral challenge with shrimp. &lt;i&gt;Results:&lt;\/i&gt; Neither patient nor control had become sensitized to shrimp allergens at the end of the study period. Both patients and controls reported the regular intake of crustaceans and\/or molluscs. &lt;i&gt;Conclusion:&lt;\/i&gt; Injection SIT with house dust mite extracts does not seem to induce de novo tropomyosin sensitization in mite-allergic patients.<\/jats:p>","DOI":"10.1159\/000085105","type":"journal-article","created":{"date-parts":[[2005,4,15]],"date-time":"2005-04-15T12:40:32Z","timestamp":1113568832000},"page":"62-65","source":"Crossref","is-referenced-by-count":25,"title":["Lack of de novo Sensitization to Tropomyosin in a Group of Mite-Allergic Patients Treated by House Dust Mite-Specific Immunotherapy"],"prefix":"10.1159","volume":"137","author":[{"given":"Riccardo","family":"Asero","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,5,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1993.tb04754.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1997.tb01251.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199908123410702"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2888%2990017-6"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2002.13248.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291521-4141%28199906%2929%3A06%3C2026%3A%3AAID-IMMU2026%3E3.0.CO%3B2-2"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2222.1987.tb02051.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2F0021-8707%2858%2990034-0"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1990.tb01092.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1992.tb02057.x"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2896%2980012-1"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1159%2F000236803"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159%2F000024201"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000065172"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2894%2990156-2"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1996.tb00043.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2003.00250.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1398-9995.1993.tb02174.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1067%2Fmai.2002.121311"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2002.23575_12.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2889%2990300-X"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016%2F0091-6749%2894%2990070-1"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2897%2970125-8"}],"container-title":["International Archives of Allergy and Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85105","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:11Z","timestamp":1745466551000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000085105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":23,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2005,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000085105","archive":["Portico"],"relation":{},"ISSN":["1018-2438","1423-0097"],"issn-type":[{"type":"print","value":"1018-2438"},{"type":"electronic","value":"1423-0097"}],"subject":[],"published":{"date-parts":[[2005]]}}}