{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,13]],"date-time":"2025-10-13T01:25:19Z","timestamp":1760318719186,"version":"3.40.4"},"reference-count":11,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>Cyanotic breath-holding spell is a benign and self-limiting disease of young children but occasionally associated with sudden, unexpected death. The authors report a rare case in a 2-year-old girl with a severe form that started after radical resection of a cervicomedullary ganglioglioma. She was admitted to our hospital because of delayed and unstable gait. Since magnetic resonance imaging showed a cervicomedullary tumor, she underwent a radical resection and histology showed the tumor to be a ganglioglioma. Postoperatively, the function of the lower cranial nerves and cerebellum deteriorated and hemiparesis on the left became apparent, but she returned to the preoperative state in a few months. In addition, mild sleep apnea (Ondine curse) and severe cyanotic breath-holding spells occurred. The former responded to medication but the latter failed and continued several times per day with a rapid onset and progression of hypoxemia, loss of consciousness, sweating and opisthotonos. Five months after the operation, the patient returned home with a portable oxygen saturation monitor equipped with an alarm. This case indicates that cyanotic breath-holding spell, as well as sleep apnea, is critical during the early postoperative period. This is the first report observing that such spells may occur as a complication of radical resection of a cervicomedullary tumor.<\/jats:p>","DOI":"10.1159\/000085163","type":"journal-article","created":{"date-parts":[[2005,6,7]],"date-time":"2005-06-07T14:20:11Z","timestamp":1118154011000},"page":"93-97","source":"Crossref","is-referenced-by-count":7,"title":["Cyanotic Breath-Holding Spell: A Life-Threatening Complication after Radical Resection of a Cervicomedullary Ganglioglioma"],"prefix":"10.1159","volume":"41","author":[{"given":"Hironori","family":"Fujisawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuya","family":"Yoshida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yo","family":"Niida","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mitsuhiro","family":"Hasegawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junkoh","family":"Yamashita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,5,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1159%2F000120604"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.65.9.953"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2F0887-8994%2896%2900006-9"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1177%2F088307380001500705"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00000433-198708020-00013"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1469-8749.1987.tb08824.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2FBF01617895"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177%2F088307380101601012"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.81.3.261"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000121219"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.107.2.265"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85163","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85163","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:35Z","timestamp":1745466575000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000085163"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000085163","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"type":"print","value":"1016-2291"},{"type":"electronic","value":"1423-0305"}],"subject":[],"published":{"date-parts":[[2005]]}}}