{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:51:44Z","timestamp":1761580304127,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2005]]},"abstract":"<i>Background:<\/i> The reliability of critical closing pressure (CrCP) estimates derived from peripheral blood pressure (BP) measurements is unclear. We attempted to evaluate the influences of peripheral circulation on determining CrCP. <i>Methods:<\/i> Twenty-five young healthy volunteers were studied. BP waves were obtained with plethysmography (Portapres) and carotid applanatory tonometry, respectively, for analysis. Transcranial Doppler was used to monitor cerebral flow velocity. Using linear regression analysis, beat-to-beat CrCP was calculated at rest, during voluntary hyperventilation and during 5% CO<sub>2<\/sub> inhalation. <i>Results:<\/i> Twenty of 25 participants demonstrating satisfactory tonometric tracings for both tests were included in the analysis. The systolic BP measured using plethysmography was higher than that derived from tonometry (139.4 \u00b1 24.7 vs. 105.5 \u00b1 29.6, p < 0.001). CrCP values derived from tonometry were all positive and higher than CrCP values derived from plethysmography (62.9 \u00b1 19.9 vs. 11.1 \u00b1 17.8, p < 0.001). The changes in CrCP induced by 5% CO<sub>2<\/sub> inhalation and hyperventilation had a correlation between two BP monitoring methods (r = 0.52, p = 0.001). <i>Conclusions:<\/i> Pressure waveform is an important determinant in calculating CrCP by linear regression analysis. The relative changes in CrCP induced by hemodynamic challenges remained a relevant indicator of cerebrovascular regulation regardless of the methods used for non-invasive BP recording.<\/jats:p>","DOI":"10.1159\/000085204","type":"journal-article","created":{"date-parts":[[2005,4,18]],"date-time":"2005-04-18T08:42:47Z","timestamp":1113813767000},"page":"369-375","source":"Crossref","is-referenced-by-count":2,"title":["Comparison of Critical Closing Pressures Extracted from Carotid Tonometry and Finger Plethysmography"],"prefix":"10.1159","volume":"19","author":[{"given":"Hung-Yi","family":"Hsu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A-Ching","family":"Chao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying-Tsung","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wen-Jang","family":"Wong","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chang-Ming","family":"Chern","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Chi","family":"Hsu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jon-Son","family":"Kuo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Han-Hwa","family":"Hu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,6,23]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS1350-4533%2803%2900027-4"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F00008506-200007000-00002"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.1974.41.5.0590"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000077927.63758.B6"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000016079"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1042%2FCS20010021"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00000542-200203000-00014"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fjnnp.66.5.606"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2007-979748"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1088%2F0967-3334%2F14%2F4%2F002"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2281.2000.00262.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007%2Fs007010050422"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2F0301-5629%2896%2900024-5"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fclc.4960231108"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2F0301-5629%2888%2990176-7"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000125303.07282.df"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2044.1991.tb09922.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1109%2F10.387192"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85204","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/85204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:49:48Z","timestamp":1745466588000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000085204"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":18,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2005,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000085204","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2005]]}}}