{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T17:44:07Z","timestamp":1785001447551,"version":"3.55.0"},"reference-count":27,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Atopic dermatitis of the head and neck (HNAD) has been recognized as a separate entity. &lt;i&gt;Malassezia furfur&lt;\/i&gt;, a lipophilic yeast, is considered to be a pathogenic allergen in this form of atopic dermatitis. &lt;i&gt;Objective:&lt;\/i&gt; The purpose of this study was to determine the level of IgE anti-&lt;i&gt;M.-furfur&lt;\/i&gt; antibodies and their relation to the severity of the disease. &lt;i&gt;Methods:&lt;\/i&gt; IgE anti-&lt;i&gt;M.-furfur&lt;\/i&gt; antibodies were assayed in 106 patients with HNAD. Controls included 25 patients with non-HNAD, 20 with nonatopic dermatitis and 16 with seborrheic dermatitis (including 4 with AIDS). &lt;i&gt;Results:&lt;\/i&gt; There was a highly significant correlation between the level of anti-&lt;i&gt;M.-furfur&lt;\/i&gt; IgE and clinical severity. Furthermore, there was a significant but smaller correlation between total IgE and clinical severity. In patients with HNAD, total IgE was higher amongst men. &lt;i&gt;Conclusion:&lt;\/i&gt; IgE anti-&lt;i&gt;M.-furfur&lt;\/i&gt; antibodies are a good and specific marker for HNAD. IgE &lt;i&gt;M. furfur&lt;\/i&gt; levels are strongly correlated with the severity of the disease.<\/jats:p>","DOI":"10.1159\/000086438","type":"journal-article","created":{"date-parts":[[2005,8,5]],"date-time":"2005-08-05T12:17:04Z","timestamp":1123244224000},"page":"107-113","source":"Crossref","is-referenced-by-count":53,"title":["Head and Neck Atopic Dermatitis and &lt;i&gt;Malassezia-furfur&lt;\/i&gt;-Specific IgE Antibodies"],"prefix":"10.1159","volume":"211","author":[{"given":"O.","family":"Bayrou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Pecquet","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Flahault","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Artigou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Abuaf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Leynadier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,8,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2000.00115.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2899%2970051-5"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0536.1996.tb02262.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2001.117015.24"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2001.117012"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.1999.00089.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000053860"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128%2FCMR.15.4.545-563.2002"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1994.tb08530.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0190-9622%2890%2970100-V"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.126.5.627"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS1081-1206%2810%2962821-9"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2230.1999.00460.x"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2000.00782.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2003.05093.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2222.1998.00248.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1991.tb14745.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2805%2980039-9"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00373427"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2FS0091-6749%2899%2970024-2"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1080%2F000155500459303"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2222.2000.00702.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1080%2F714030958"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1468-3083.2001.00207.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1398-9995.2001.056006512.x"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1468-3083.2004.00963.x"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1159%2F000069968"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86438","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86438","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:12:11Z","timestamp":1745464331000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000086438"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":27,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2005,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000086438","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}