{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,10]],"date-time":"2026-02-10T19:47:38Z","timestamp":1770752858418,"version":"3.50.0"},"reference-count":17,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Respiration"],"published-print":{"date-parts":[[2005]]},"abstract":"<i>Background:<\/i> Noninvasive bilevel positive pressure ventilation (N-BiPAP) has an established role in providing respiratory support in patients with acute respiratory failure. The significant advantage of N-BiPAP is to avoid endotracheal intubation and its complications. Currently there are no data that support N-BiPAP as first-line treatment in patients with blunt thoracic trauma. <i>Objective:<\/i> To evaluate the safety and efficacy of N-BiPAP in patients with acute respiratory failure due to blunt thoracic trauma. <i>Methods:<\/i> Prospective observational study. Twenty-two patients with blunt chest trauma (mean injury severity score 26 \u00b1 9) were studied. N-BiPAP was applied via a tight-fitting full or total-face mask, combined with regional anesthesia in all patients. <i>Results:<\/i>N-BiPAP resulted in significant changes in blood gasses, heart rate and breathing frequency at 1 h. Eighteen out of 22 patients avoided intubation and were discharged from the ICU (success group). Four patients met predefined criteria and required intubation (failure group) within 24 h after N-BiPAP. Three of the patients in the failure group survived while 1 developed septic shock and died. The acute response of oxygenation to N-BiPAP differed significantly between groups, being higher in the success group. Complications related to N-BiPAP were minor, consisting of nose bridge injury (1 patient) and gastric distention (1 patient). <i>Conclusions:<\/i> N-BiPAP administration could be a safe and effective method to improve the gas exchange in patients with acute respiratory failure due to blunt thoracic trauma.<\/jats:p>","DOI":"10.1159\/000086501","type":"journal-article","created":{"date-parts":[[2005,8,19]],"date-time":"2005-08-19T10:02:00Z","timestamp":1124445720000},"page":"517-522","source":"Crossref","is-referenced-by-count":32,"title":["Noninvasive Bilevel Positive Pressure Ventilation in Patients with Blunt Thoracic Trauma"],"prefix":"10.1159","volume":"72","author":[{"given":"N.","family":"Xirouchaki","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Kondoudaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Anastasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Alexopoulou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Koumiotaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Georgopoulos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,9,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-198203000-00008"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TA.0000053197.40145.62"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00134-003-1813-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.97.4.943"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-198508000-00006"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.284.18.2352"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM200102153440703"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1164%2Frccm.200301-072OC"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000076676"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136%2Fthorax.57.3.192"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-197403000-00001"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.270.24.2957"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.101.6.1481"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00005373-200009000-00018"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2F0020-1383%2886%2990151-8"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.284.18.2361"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00134-001-1114-4"}],"container-title":["Respiration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86501","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86501","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:13:00Z","timestamp":1745464380000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000086501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":17,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2005,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000086501","archive":["Portico"],"relation":{},"ISSN":["0025-7931","1423-0356"],"issn-type":[{"value":"0025-7931","type":"print"},{"value":"1423-0356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}