{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:46:20Z","timestamp":1761630380855,"version":"3.40.4"},"reference-count":29,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Skin Pharmacol Physiol"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>Beta-blocking medications are rarely associated with drug-induced lupus erythematosus syndrome and have never been incriminated as a cause of subacute lupus erythematosus (SCLE). We present herein the first case of SCLE induced by acebutolol. A 57-year-old woman presented with a 1-month history of a cutaneous eruption of the photoexposed areas. One month ago, the patient had started a treatment with oral acebutolol to cure a hypertension of 1-year evolution. Physical examination revealed erythematous scaly annular plaques, involving the face, arms and trunk. Immunologic serology findings revealed a positive titer of antinuclear antibodies up to 1\/1,280 with positivity of antihistone and Ro\/SSA antibodies. Acebutolol was stopped, and the lesions cleared completely 4 months later. Literature data, along with our case, suggest a link between acebutolol therapy and the onset of a lupus syndrome. Although this is the first report of acebutolol-induced SCLE, we should be aware of this occurrence, and avoidance of acebutolol is recommended in patients with stigmata of lupus erythematosus<\/jats:p>","DOI":"10.1159\/000086668","type":"journal-article","created":{"date-parts":[[2005,7,6]],"date-time":"2005-07-06T08:40:24Z","timestamp":1120639224000},"page":"230-233","source":"Crossref","is-referenced-by-count":27,"title":["Acebutolol-Induced Subacute Cutaneous Lupus Erythematosus"],"prefix":"10.1159","volume":"18","author":[{"given":"S.","family":"Fenniche","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Dhaoui","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.","family":"Ben Ammar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.","family":"Benmously","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Marrak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"I.","family":"Mokhtar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,8,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198806023182209"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2165%2F00002018-199512040-00008"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.115.12.1409"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2896%2990315-1"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.2.5864.452"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1136%2Fjcp.30.8.770"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2230.1982.tb02414.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fpgmj.57.665.189"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.1.6178.1603"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2897%2970009-4"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.2165%2F00003495-198019040-00004"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198806023182209"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.120.3.321"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136%2Fpgmj.46.542.729"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F00005792-196905000-00002"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1084%2Fjem.134.1.294"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2880%2991554-8"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3109%2F03602539408998315"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.7725110"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.7973636"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016%2FS0046-8177%2897%2990281-1"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.1998.2576q.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2001.114565"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2889%2980031-3"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2896%2990315-1"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1191%2F096120398678920244"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2895%2990392-5"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2805%2979887-1"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0560.1999.tb01809.x"}],"container-title":["Skin Pharmacology and Physiology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86668","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/86668","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:13:44Z","timestamp":1745464424000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000086668"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":29,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2005,10,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000086668","archive":["Portico"],"relation":{},"ISSN":["1660-5527","1660-5535"],"issn-type":[{"type":"print","value":"1660-5527"},{"type":"electronic","value":"1660-5535"}],"subject":[],"published":{"date-parts":[[2005]]}}}