{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T21:07:36Z","timestamp":1789679256136,"version":"4.0.1"},"reference-count":11,"publisher":"S. Karger AG","issue":"6","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To describe fundus autofluorescence (AF), fluorescein angiography (FA) and indocyanine green angiography (ICGA) in different types of retinal astrocytic hamartomas in tuberous sclerosis (Morbus Bourneville-Pringle). &lt;i&gt;Methods:&lt;\/i&gt; Two eyes with 8 lesions, i.e. type 1 (n = 7) and type 3 (n = 1), were examined. AF pictures were taken prior to injection, FA and ICGA images were obtained in the early and the late phase. To achieve additional cases, a systematic literature review with exten- sive Internet and library search was performed. &lt;i&gt;Results: &lt;\/i&gt; Strong AF was seen in type 2 and type 3 retinal astrocytic hamartomas, whereas type 1 lesions blocked the physiologic fundus AF. Fluorescence angiography of all types of lesions revealed hypofluorescence in early frames and hyperfluorescence originating from leakage in late frames. ICGA showed a subtle blockade in type 1, a total blockade in type 2 and in the central part and a partial blockade in the peripheral part in type 3 lesions. &lt;i&gt;Conclusions:&lt;\/i&gt; Retinal astrocytic hamartomas in tuberous sclerosis can be easily detected by angiography, especially type 1 lesions which are difficult to visualize by funduscopy. Early- and late-phase fluorescein angiography and ICGA are helpful to differentiate the three lesion types.<\/jats:p>","DOI":"10.1159\/000088377","type":"journal-article","created":{"date-parts":[[2005,11,15]],"date-time":"2005-11-15T07:33:49Z","timestamp":1132040029000},"page":"350-356","source":"Crossref","is-referenced-by-count":44,"title":["Autofluorescence and Angiographic Findings of Retinal Astrocytic Hamartomas in Tuberous Sclerosis"],"prefix":"10.1159","volume":"219","author":[{"given":"Stefan","family":"Mennel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carsten H.","family":"Meyer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fred","family":"Eggarter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Peter","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2005,11,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.85.4.420"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0161-6420%2899%2990133-1"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9394%2801%2901429-5"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2008-1035068"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-198400440-00005"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00006982-198600610-00004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2008-1054423"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.57.10.773"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F00004397-197201210-00007"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0039-6257%2885%2990058-X"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136%2Fbjo.87.11.1381"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/88377","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/88377","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:30:33Z","timestamp":1745465433000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000088377"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":11,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2005,11,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000088377","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}