{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T20:31:26Z","timestamp":1772915486323,"version":"3.50.1"},"reference-count":24,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2005,1,1]],"date-time":"2005-01-01T00:00:00Z","timestamp":1104537600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"published-print":{"date-parts":[[2005]]},"abstract":"<jats:p>Seventy-three patients were evaluated for the changes in pain relief, numbness and paresthesias after Gamma Knife radiosurgery to a maximum dose of 76\u201387 Gy for trigeminal neuralgia. Patients experienced pain relief as follows: 59% attained complete pain relief without prior surgery (33% with prior surgery); 25% achieved \u226750% pain reduction (28% with prior surgery); 11% of surgery patients obtained minor pain relief, and 16% of patients without surgery had no relief (28% with prior surgery). Level of pain decreased rapidly within 6 weeks after radiosurgery. Numbness\/paresthesias developed slowly over the first 12\u201315 months. Bothersome levels were experienced by 15% of the patients without prior surgery (22% with prior surgery). Comparison of the occurrence of numbness\/paresthesias, with respect to prior surgery, was not statistically significant. Only 2% of all patients had persistently bothersome side effects. In conclusion, radiosurgery is an effective treatment of trigeminal neuralgia, especially for those patients not having prior surgery.<\/jats:p>","DOI":"10.1159\/000088655","type":"journal-article","created":{"date-parts":[[2005,10,10]],"date-time":"2005-10-10T13:31:15Z","timestamp":1128951075000},"page":"148-152","source":"Crossref","is-referenced-by-count":19,"title":["Gamma Knife Radiosurgery for Trigeminal Neuralgia: The Washington University Initial Experience"],"prefix":"10.1159","volume":"83","author":[{"given":"Robert E.","family":"Drzymala","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert S.","family":"Malyapa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joshua L.","family":"Dowling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keith M.","family":"Rich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joseph R.","family":"Simpson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"David B.","family":"Mansur","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2005,12,16]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-200206000-00015"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2004.100.5.0848"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2000.93.1.0147"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0360-3016%2801%2901606-6"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1159%2F000029771"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-200203000-00012"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000069503"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1440-1673.1999.433668.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000099734"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000056421"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001%2Farchneur.55.12.1524"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00002508-200201000-00007"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2001.94.1.0014"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2004.100.4.0597"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0360-3016%2803%2900264-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-200107000-00008"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2002.97.2.0347"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159%2F000056424"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2001.95.2.0199"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016%2FS0360-3016%2800%2900513-7"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1159%2F000056423"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1159%2F000056422"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159%2F000056492"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1118%2F1.1501138"}],"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/88655","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/88655","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:32:47Z","timestamp":1745465567000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000088655"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":24,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2005,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000088655","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[2005]]}}}