{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,27]],"date-time":"2025-10-27T15:52:45Z","timestamp":1761580365808,"version":"3.40.4"},"reference-count":21,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2006]]},"abstract":"<i>Introduction:<\/i> This study was undertaken to investigate the effects of two different \u03b1<sub>1<\/sub>-adrenergic blockers on bladder hypertrophy using ultrasound-estimated bladder weight (UEBW) and to assess the relation between changes in UEBW and other objective and subjective parameters of disease severity in patients with benign prostatic hyperplasia (BPH). <i>Materials and Methods:<\/i> 41 men were enrolled in the study and they were subjected to either watchful waiting (group 1) or \u03b1<sub>1<\/sub>-adrenergic receptor blocker therapy (group 2 with alfuzosin; group 3 with tamsulosin). The patients were investigated by symptom evaluation using the International Prostate Symptom Score (IPSS) and quality of life score (QOL), uroflowmetry and UEBW. The parameters were assessed again 3 months after initiation of treatment and compared with the initial values. <i>Results:<\/i> While the mean UEBW increased in group 1 (42.2 \u00b1 10.3 to 52.5 \u00b1 12.2 g), it decreased in both the other groups that received \u03b1-blocker therapy (61.3 \u00b1 18.7 to 41.1 \u00b1 13.2 and 59.4 \u00b1 17.2 to 43.5 \u00b1 17.6 g, respectively). In groups 2 and 3, the mean UEBW, post-void residual urine, IPSS and QOL values decreased, and the mean maximum flow rate increased. All of the changes in group 2 and all except QOL in group 3 were statistically significant (p < 0.05). The changes correlated well with each other with regard to treatment success. The highest decreases in UEBW were encountered in patients with heavier bladders. <i>Conclusions:<\/i> UEBW decreases with \u03b1<sub>1<\/sub>-adrenergic receptor blockers. When used together with the other objective and subjective parameters, UEBW is a promising quantitative parameter as a follow-up tool and can be useful in monitoring the therapeutic effects of \u03b1<sub>1<\/sub>-adrenergic receptor blockers.<\/jats:p>","DOI":"10.1159\/000089734","type":"journal-article","created":{"date-parts":[[2006,1,6]],"date-time":"2006-01-06T10:43:21Z","timestamp":1136544201000},"page":"42-50","source":"Crossref","is-referenced-by-count":13,"title":["Effects of Selective Alpha-1-Adrenergic Receptor Blockers on Bladder Weight"],"prefix":"10.1159","volume":"76","author":[{"given":"Tulga","family":"Egilmez","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mir Ali","family":"Pourbagher","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sezgin","family":"Guvel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ferhat","family":"Kilinc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tahsin","family":"Turunc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Ozkardes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2006,1,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291520-6777%281998%2917%3A2%3C99%3A%3AAID-NAU3%3E3.0.CO%3B2-7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199605000-00032"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199803000-00035"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2F1520-6777%282000%2919%3A5%3C585%3A%3AAID-NAU5%3E3.0.CO%3B2-U"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2FS0090-4295%2896%2900059-3"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.1985.tb06299.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199702000-00016"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002%2F1520-6777%282000%2919%3A5%3C609%3A%3AAID-NAU7%3E3.0.CO%3B2-H"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291520-6777%281999%2918%3A6%3C659%3A%3AAID-NAU17%3E3.0.CO%3B2-C"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097%2F01.ju.0000081460.23737.63"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1023%2FA%3A1006973412237"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2F%28SICI%291520-6777%282000%2919%3A1%3C29%3A%3AAID-NAU5%3E3.0.CO%3B2-%23"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-200007000-00045"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199903000-00025"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199707000-00024"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-200210010-00095"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199809010-00092"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-200203000-00090"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.pcan.4500410"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199503000-00034"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.1979.tb02846.x"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/89734","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/89734","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:43:47Z","timestamp":1745466227000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000089734"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":21,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2006,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000089734","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"type":"print","value":"0042-1138"},{"type":"electronic","value":"1423-0399"}],"subject":[],"published":{"date-parts":[[2006]]}}}