{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T01:51:38Z","timestamp":1787017898762,"version":"build-2736575974"},"reference-count":17,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Neonatology"],"published-print":{"date-parts":[[2006]]},"abstract":"<i>Background:<\/i> Cardiac troponins T (cTnT) and I (cTnI) are <i>well-established <\/i>markers in detecting myocardial ischemic damage in adults. Perinatal asphyxia is associated with cardiac dysfunction. <i>Objectives:<\/i> To evaluate serum concentrations of cTnI in asphyxiated neonates and to investigate whether cTnI is correlated with the traditional markers of asphyxia. <i>Methods:<\/i> Blood samples were collected from 13 asphyxiated neonates (umbilical artery pH <7.18 and either a 1-min Apgar score <4 or a 5-min Apgar score <7) and 39 controls. Data on gestation, birth weight, sex, Apgar scores, mode of delivery, umbilical pH, creatinine, serum activity of aspartate and alanine aminotransferase, and QTc interval were investigated. <i>Results:<\/i> Median (range) cTnI concentrations were significantly higher in asphyxiated neonates with respect to healthy infants: 0.36 \u00b5g\/l (0.05\u201311) versus 0.04 \u00b5g\/l (0.04\u20130.06); p < 0.01. In asphyxiated babies, no statistically significant correlations were found between concentrations of cTnI and the other markers of asphyxia. <i>Conclusions:<\/i> In asphyxiated neonates, cTnI concentrations are higher with respect to healthy infants, suggesting the presence of myocardial damage in this group of high-risk patients. cTnI does not correlate with the traditional markers of asphyxia.<\/jats:p>","DOI":"10.1159\/000089795","type":"journal-article","created":{"date-parts":[[2006,2,2]],"date-time":"2006-02-02T04:34:37Z","timestamp":1138854877000},"page":"190-193","source":"Crossref","is-referenced-by-count":41,"title":["Cardiac Troponin I in Asphyxiated Neonates"],"prefix":"10.1159","volume":"89","author":[{"given":"Daniele","family":"Trevisanuto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giorgio","family":"Picco","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosanna","family":"Golin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicoletta","family":"Doglioni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Altinier","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martina","family":"Zaninotto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Zanardo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,4,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.58.8.605"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3476%2885%2980417-0"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-3476%2879%2980841-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000242765"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1651-2227.1985.tb11036.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2F0009-9120%2894%2900065-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080%2F713794580"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fadc.2002.025478"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1080%2F08035250310006584"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1159%2F000013999"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1515%2FCCLM.2000.051"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0735-1097%2800%2900804-4"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159%2F000013973"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1159%2F000079068"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2004-823775"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159%2F000080890"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-8703%2898%2970148-6"}],"container-title":["Neonatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/89795","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/89795","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:44:39Z","timestamp":1745451879000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000089795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":17,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2006,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000089795","archive":["Portico"],"relation":{},"ISSN":["1661-7800","1661-7819"],"issn-type":[{"value":"1661-7800","type":"print"},{"value":"1661-7819","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}