{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T20:36:33Z","timestamp":1773952593511,"version":"3.50.1"},"reference-count":14,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2006]]},"abstract":"<i>Objective:<\/i> To determine the risk of ventriculoperitoneal (VP) shunt infections after percutaneous retrograde gastrostomy feeding tube (GT) placement in children with brain tumors. <i>Patients and Methods: <\/i>All children (age 0\u201318 years) with primary brain tumors diagnosed and treated at the Hospital for Sick Children, Toronto, Canada, were subjected to a retrospective analysis. Two groups were identified: the study group included children with a VP shunt and a GT; the control group included children with VP shunts only. Each study patient was matched with 2 controls to compare the rate of infections (cohort comparative study). <i>Results:<\/i> There were 1,167 children diagnosed and treated with primary brain tumors during the study period (1988\u20132003); 174 (15%) had a VP shunt and 23 (2%) children had both, a VP shunt and a GT. In the study group (n = 17), GTs were inserted at a median time of 80 days (range 6\u2013204 days) after VP shunts. VP shunt infection rate was 23.5% (4\/17) compared to 8.8% (3\/34) in the control group (OR 3.18; 95% CI 0.622\u201316.54, p = 0.16). Three (75%) of the infection episodes in the study group presented with an ascending VP shunt infection directly related to the GT insertion or manipulation in the first 6 weeks. These GTs were inserted at 13, 47 and 49 days after VP shunt insertion. <i>Conclusion:<\/i> Placement of percutaneous retrograde GTs, in the acute phase, in children with brain tumors and VP shunts may increase the risk of ascending meningitis especially if there are early GT-related complications.<\/jats:p>","DOI":"10.1159\/000090462","type":"journal-article","created":{"date-parts":[[2006,2,7]],"date-time":"2006-02-07T05:08:18Z","timestamp":1139288898000},"page":"95-99","source":"Crossref","is-referenced-by-count":46,"title":["Risk of Ventriculoperitoneal Shunt Infections due to Gastrostomy Feeding Tube Insertion in Pediatric Patients with Brain Tumors"],"prefix":"10.1159","volume":"42","author":[{"given":"A.","family":"Gassas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kennedy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Green","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Connolly","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Cohen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U.","family":"Dag-Ellams","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Kulkarni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E.","family":"Bouffet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2006,2,10]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2F1097-0142%28197905%2943%3A5%2B%3C2036%3A%3AAID-CNCR2820430712%3E3.0.CO%3B2-7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002%2Fmpo.2950250504"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0899-9007%2897%2900225-6"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.11598"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fcncr.11833"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000075255"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000120455"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-199808000-00068"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.2001.94.2.0195"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1086%2F368191"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002470050401"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0016-5107%2804%2900004-5"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-1999-13658"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.114.2.458"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/90462","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/90462","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T22:44:29Z","timestamp":1745448269000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000090462"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":14,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2006,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000090462","archive":["Portico"],"relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.9298.466774","asserted-by":"object"}]},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}