{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T16:43:12Z","timestamp":1790872992146,"version":"4.1.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Gynecol Obstet Invest"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>&lt;i&gt;Aims:&lt;\/i&gt; To determine whether or not serum adiponectin concentrations are influenced by ovarian hyperstimulation during in vitro fertilization (IVF). &lt;i&gt;Methods:&lt;\/i&gt; This study involved 52 women who were participating in IVF-ET cycles. Adiponectin levels in serum were determined by radioimmunoassay and compared. &lt;i&gt;Results:&lt;\/i&gt; Serum adiponectin levels fell from Day-basal to Day-hCG (p = 0.047), and then rose on Day-OR and again on Day-7ET (p &lt; 0.001; p &lt; 0.001). Estradiol levels on Day-hCG were significantly and positively correlated with serum adiponectin levels on Day-OR and Day-7ET (r = 0.325, p = 0.019; r = 0.372, p = 0.007). Progesterone levels on Day-OR positively correlated with serum adiponectin levels on Day-basal (r = 0.278, p = 0.046). There was also a positive correlation between progesterone levels on Day-7ET and serum adiponectin levels on Day-OR (r = 0.289, p = 0.038). Multiple linear regression analysis revealed that adiponectin levels on Day-OR and Day-7ET were negatively correlated with age and body mass index after adjustment was made for concomitant diseases. &lt;i&gt;Conclusions:&lt;\/i&gt; To sum up, following gonadotropin treatment, serum adiponectin levels decrease as a result of the negative effect of high estradiol levels on adiponectin production. Conversely, serum adiponectin levels increase following human chorionic gonadotropin treatment.<\/jats:p>","DOI":"10.1159\/000092260","type":"journal-article","created":{"date-parts":[[2006,3,24]],"date-time":"2006-03-24T09:46:49Z","timestamp":1143193609000},"page":"61-65","source":"Crossref","is-referenced-by-count":26,"title":["Serum Adiponectin Levels Increase after Human Chorionic Gonadotropin Treatment during in vitro Fertilization"],"prefix":"10.1159","volume":"62","author":[{"given":"Yung-Hsien","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eing-Mei","family":"Tsai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ling","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hung-Sheng","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chieh","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lee-Chen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chien-Hung","family":"Lee","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiang-Bin","family":"Jong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Te-Fu","family":"Chan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,8,11]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1074%2Fjbc.270.45.26746"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1006%2Fbbrc.1999.0255"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.51.9.2734"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038%2F90984"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.8.3815"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.5.1930"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.50.9.2094"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2004-825726"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.52.2.268"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1071%2FR98010"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS1043-2760%2801%2900524-0"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jsgi.2004.05.001"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0015-0282%2802%2903116-3"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.27.10.2450"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1161%2F01.HYP.0000078490.59735.6E"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038%2F279679a0"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1210%2Fjcem-51-6-1469"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1194%2Fjlr.M400373-JLR200"}],"container-title":["Gynecologic and Obstetric Investigation"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92260","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92260","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:02:18Z","timestamp":1745463738000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000092260"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2006,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000092260","archive":["Portico"],"relation":{},"ISSN":["0378-7346","1423-002X"],"issn-type":[{"value":"0378-7346","type":"print"},{"value":"1423-002X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}