{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T14:46:05Z","timestamp":1784904365796,"version":"3.55.0"},"reference-count":25,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>&lt;i&gt;Background: &lt;\/i&gt;There are few published data on the clinical characteristics of hyperhidrosis. &lt;i&gt;Objective:&lt;\/i&gt; To describe the functional impairment caused by primary focal hyperhidrosis. &lt;i&gt;Methods:&lt;\/i&gt; Patients with hyperhidrosis (n = 345) were enrolled at the Department of Dermatology, University of W\u00fcrzburg. Controls (n = 154) were a convenience sample of subjects without hyperhidrosis. Hyperhidrosis characteristics, health-related quality of life and functional impairment were assessed. &lt;i&gt;Results:&lt;\/i&gt; Patients with axillary hyperhidrosis reported a later age at onset and a higher prevalence of a family history of hyperhidrosis than patients with palmar hyperhidrosis. Sixty-three percent of patients reported occupational impairment related to hyperhidrosis. Hyperhidrosis patients reported emotional and physical impairment, with a greater proportion of the axillary group reporting impairment. More than 50% of patients reported moderate to extreme impairment in personal relationships and in social situations. &lt;i&gt;Conclusion:&lt;\/i&gt; Primary focal hyperhidrosis is a serious medical condition, affecting work productivity, daily activities, emotional well-being and personal relationships.<\/jats:p>","DOI":"10.1159\/000092285","type":"journal-article","created":{"date-parts":[[2006,5,26]],"date-time":"2006-05-26T13:49:21Z","timestamp":1148651361000},"page":"343-353","source":"Crossref","is-referenced-by-count":137,"title":["Primary Focal Hyperhidrosis: Disease Characteristics and Functional Impairment"],"prefix":"10.1159","volume":"212","author":[{"given":"Henning","family":"Hamm","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus K.","family":"Naumann","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan W.","family":"Kowalski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandra","family":"K\u00fctt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Kozma","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chris","family":"Teale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,5,12]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2003.12.029"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2230.2003.01162.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1468-1331.2001.00207.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0149-2918%2803%2990041-5"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.139.6.731"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2003.12.040"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.138.4.539"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2002.05059.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1524-4725.2002.01159.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1524-4725.2005.31106"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2230.1994.tb01167.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00005650-199603000-00003"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-199707000-00023"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1067%2Fmva.2002.119507"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2004.06334.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1995.tb02708.x"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2000.03830.x"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1080%2F000155500300012873"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1067%2Fmjd.2001.110880"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2001.04183.x"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.1996.d01-1102.x"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-4362.2002.01436.x"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-4362.2002.01448.x"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.1999.02767.x"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1053%2Fajcd.2002.36643"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92285","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92285","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:02:40Z","timestamp":1745463760000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000092285"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":25,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2006,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000092285","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}