{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T20:35:39Z","timestamp":1772915739441,"version":"3.50.1"},"reference-count":13,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pediatr Neurosurg"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>&lt;i&gt;Introduction:&lt;\/i&gt; Hypothalamic hamartomas are associated with precocious puberty, gelastic seizures and severe refractory epilepsy. Treatment options include surgical resection, radiofrequency and radiosurgery. &lt;i&gt;Case Report:&lt;\/i&gt; A 7-month-old girl presented with gelastic seizures and developmental delay related to a giant hypothalamic hamartoma. The patient was operated through a subfrontal approach. Intraoperatively the lesion appeared intimately adherent to the right internal carotid artery. Seizure control was improved after tumoral decompression. &lt;i&gt;Conclusions:&lt;\/i&gt; Treatment of giant hypothalamic hamartomas should always include surgical resection, given the mass effect over surrounding vital structures. Subfrontal approach with orbitary rim osteotomy provides a wide exposure with minimal frontal lobe retraction. Close adherence of hypothalamic hamartoma to vascular structures may be present, requiring careful surgical manipulation.<\/jats:p>","DOI":"10.1159\/000092365","type":"journal-article","created":{"date-parts":[[2006,5,19]],"date-time":"2006-05-19T08:22:41Z","timestamp":1148026961000},"page":"254-257","source":"Crossref","is-referenced-by-count":17,"title":["Giant Hypothalamic Hamartoma Operated through Subfrontal Approach with Orbitary Rim Osteotomy"],"prefix":"10.1159","volume":"42","author":[{"given":"Pablo","family":"Miranda","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Javier","family":"Esparza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonio","family":"Cabrera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jose","family":"Hinojosa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2006,5,24]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1002%2Fana.410230502"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000055990"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.1999.91.2.0212"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-199406000-00001"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F116.4.757"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093%2Fbrain%2F118.1.279"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2F0013-4694%2895%2900063-5"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007%2FBF00263190"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1528-1157.1994.tb02470.x"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002%2Fana.410420111"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3171%2Fjns.1999.91.5.0881"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097%2F00006123-200012000-00014"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0887-8994%2800%2900170-3"}],"container-title":["Pediatric Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92365","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/92365","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:03:22Z","timestamp":1745463802000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000092365"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":13,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2006,5,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000092365","archive":["Portico"],"relation":{},"ISSN":["1016-2291","1423-0305"],"issn-type":[{"value":"1016-2291","type":"print"},{"value":"1423-0305","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}