{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:57:20Z","timestamp":1745470640655,"version":"3.40.4"},"reference-count":10,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2006]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; It is uncertain whether recurrent transient ischemic attacks (R-TIAs), when comparing with single TIAs (S-TIAs), have any distinct mechanisms. &lt;i&gt;Methods:&lt;\/i&gt; All consecutive patients with TIAs, who had been admitted for a 2-year period, were divided into two groups: those who had R-TIAs and those who had S-TIAs. Registry data, medical records, and imaging findings were reviewed and compared between the two groups. &lt;i&gt;Results:&lt;\/i&gt; There were 85 patients who had TIAs: 42 patients had R-TIAs, and 43 patients had S-TIAs. On univariate analysis, R-TIA patients had less cardiac embolic TIA sources, less weakness, less speech disturbances, shorter symptom duration, a longer time interval from onset to treatment, less abnormalities on diffusion-weighted magnetic resonance imaging, and more significant relevant arterial stenoses. After logistic regression analysis, independent factors associated with R-TIAs were symptom duration &lt;10 min (odds ratio OR 3.62; 95% confidence interval CI 1.37\u20139.57), \u226750% stenosis of the clinically relevant artery (OR 7.08; 95% CI 1.29\u201338.71), and absence of cardiac embolic sources (OR 0.04; 95% CI 0.002\u20130.71). &lt;i&gt;Conclusions:&lt;\/i&gt; R-TIAs may have pathophysiological mechanisms distinct from those of S-TIAs and so may provide a clue for the etiologic diagnosis, in that patients with R-TIAs are more likely to have large-artery atherosclerosis.<\/jats:p>","DOI":"10.1159\/000094010","type":"journal-article","created":{"date-parts":[[2006,6,21]],"date-time":"2006-06-21T06:15:18Z","timestamp":1150870518000},"page":"240-244","source":"Crossref","is-referenced-by-count":6,"title":["Predictive Implications of Recurrent Transient Ischemic Attacks in Large-Artery Atherosclerosis"],"prefix":"10.1159","volume":"22","author":[{"given":"Seo Hyun","family":"Kim","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sang Won","family":"Han","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ji Hoe","family":"Heo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2006,8,30]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1001%2Farchneur.60.2.280"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000047697"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.157.21.2413"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.285.19.2486"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM197702172960703"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00004728-200103000-00017"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1148%2Fradiol.2242011302"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0735-1097%2803%2900901-X"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1159%2F000065662"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9149%2891%2990382-U"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/94010","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/94010","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:27:25Z","timestamp":1745461645000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000094010"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":10,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2006,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000094010","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2006]]}}}