{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T02:50:05Z","timestamp":1778554205021,"version":"3.51.4"},"reference-count":39,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T00:00:00Z","timestamp":1165536000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T00:00:00Z","timestamp":1165536000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Psychother Psychosom"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To examine the association between separation anxiety disorder (SAD) and mental disorders in a community sample and to evaluate whether separation anxiety is specifically related to panic disorder with and without agoraphobia. &lt;i&gt;Method:&lt;\/i&gt; The data come from a 4-year, prospective longitudinal study of a representative cohort of adolescents and young adults aged 14\u201324 years at baseline in Munich, Germany. The present analyses are based on a subsample of the younger cohort that completed baseline and two follow-up investigations (n = 1,090). DSM-IV diagnoses were made using the Munich Composite International Diagnostic Interview. Cox regressions with time-dependent covariates were used to examine whether prior SAD is associated with an increased risk for subsequent mental disorders. &lt;i&gt;Results:&lt;\/i&gt; Participants meeting DSM-IV criteria for SAD were at an increased risk of developing subsequent panic disorder with agoraphobia (PDAG) (HR = 18.1, 95% CI = 5.6\u201358.7), specific phobia (HR = 2.7, 95% CI = 1.001\u20137.6), generalized anxiety disorder (HR = 9.4, 95% CI = 1.8\u201348.7), obsessive-compulsive disorder (HR = 10.7, 95% CI = 1.7\u201366.1), bipolar disorder (HR = 7.7, 95% CI = 2.8\u201320.8), pain disorder (HR = 3.5, 95% CI = 1.3\u20139.1), and alcohol dependence (HR = 4.7, 95% CI = 1.7\u201312.4). Increased hazard rates for PDAG (HR = 4.2, 95% CI = 1.4\u201312.1), bipolar disorder type II (HR = 8.1, 95% CI = 2.3\u201327.4), pain disorder (HR = 1.9, 95% CI = 1.01\u20133.5), and alcohol dependence (HR = 2.1, 95% CI = 1.1\u20134.) were also found for subjects fulfilling subthreshold SAD. &lt;i&gt;Conclusions:&lt;\/i&gt; Although revealing a strong association between SAD and PDAG, our results argue against a specific SAD-PDAG relationship. PDAG was neither a specific outcome nor a complete mediator variable of SAD.<\/jats:p>","DOI":"10.1159\/000096364","type":"journal-article","created":{"date-parts":[[2006,12,8]],"date-time":"2006-12-08T14:31:12Z","timestamp":1165588272000},"page":"47-56","source":"Crossref","is-referenced-by-count":136,"title":["Childhood Separation Anxiety and the Risk of Subsequent Psychopathology: Results from a Community Study"],"prefix":"10.1159","volume":"76","author":[{"given":"Tanja 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