{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T04:34:33Z","timestamp":1784867673004,"version":"3.55.0"},"reference-count":13,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2006,12,18]],"date-time":"2006-12-18T00:00:00Z","timestamp":1166400000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,12,18]],"date-time":"2006-12-18T00:00:00Z","timestamp":1166400000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ophthalmologica"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Purpose:&lt;\/i&gt; It was the aim of this study to evaluate antiphospholipid antibodies (APA), i.e. lupus anticoagulants (LA) and anticardiolipin (ACA) IgG and IgM, in ophthalmic occlusive disease. &lt;i&gt;Methods:&lt;\/i&gt; Over a 3.5-year period, APA were evaluated in 368 patients. &lt;i&gt;Results:&lt;\/i&gt; Eighty-six patients (23.4%), compared to 5% in the general population, tested positive for APA. APA did not differ significantly between patients with venous (20.6%) or arterial (25.5%) occlusive disease. This included 93 patients with central retinal vein occlusion (18% APA positive), 67 with retinal branch vein occlusion (24% APA positive), 41 with central retinal artery occlusion (22% APA positive), 53 with retinal branch artery occlusion (32% APA positive), 71 with anterior ischemic optic neuropathy (23% APA positive), 12 with posterior ischemic optic neuropathy (33% APA positive) and 31 patients with amaurosis fugax (23% APA positive). Excluding patients with accepted main risk factors, APA were positive in 15.3% of 85 patients. &lt;i&gt;Conclusion:&lt;\/i&gt; The high APA prevalence confirms its relevance in ocular occlusive disorders.<\/jats:p>","DOI":"10.1159\/000096521","type":"journal-article","created":{"date-parts":[[2006,12,22]],"date-time":"2006-12-22T23:18:32Z","timestamp":1166829512000},"page":"41-46","source":"Crossref","is-referenced-by-count":30,"title":["Antiphospholipid Antibodies in Ocular Arterial and Venous Occlusive Disease"],"prefix":"10.1159","volume":"221","author":[{"given":"Anja M.","family":"Palmowski-Wolfe","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elke","family":"Denninger","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J\u00fcrgen","family":"Geisel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Pindur","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Klaus W.","family":"Ruprecht","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,12,18]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0039-6257%2802%2900289-8"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182%2Fblood-2002-02-0441"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1191%2F096120398678919688"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093%2Fqjmed%2F91.2.125"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0049-3848%2896%2900119-3"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9394%2899%2900311-6"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1159%2F000050862"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1023%2FA%3A1001795918894"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177%2F107602960100700401"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2FS0161-6420%2899%2990159-8"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007%2Fs004170050138"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1023%2FA%3A1001131323739"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0049-0172%2899%2980029-8"}],"container-title":["Ophthalmologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/96521","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/96521","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:53:50Z","timestamp":1745463230000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000096521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,12,18]]},"references-count":13,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2006,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000096521","archive":["Portico"],"relation":{},"ISSN":["0030-3755","1423-0267"],"issn-type":[{"value":"0030-3755","type":"print"},{"value":"1423-0267","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,12,18]]}}}