{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T18:46:43Z","timestamp":1791139603792,"version":"4.1.0"},"reference-count":21,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,1,1]],"date-time":"2006-01-01T00:00:00Z","timestamp":1136073600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Am J Nephrol"],"published-print":{"date-parts":[[2006]]},"abstract":"<i>Background:<\/i> Blood pressure (BP) measured outside the clinic correlates better with cardiovascular outcomes in patients with essential hypertension. To assess the role of out-of-clinic BP recordings in predicting cardiovascular events in patients with chronic kidney disease (CKD), a prospective cohort study was conducted in 217 veterans with CKD. <i>Methods:<\/i> BP was measured outside the clinic at home and by 24-hour ambulatory recordings, and in the clinic by \u2018routine\u2019 and standardized methods. Patients were followed over a median of 3.4 years to assess the combined end-point of total mortality, myocardial infarction or stroke. <i>Results:<\/i> Average (\u00b1SD) home BP was 147.0 \u00b1 21.4\/78.3 \u00b1 11.6 mm Hg, 24-hour ambulatory BP 133.5 \u00b1 16.6\/73.1 \u00b1 11.1 mm Hg and in-clinic BPs were 155.2 \u00b1 25.6\/84.7 \u00b1 14.2 mm Hg by the standardized method, and 144.5 \u00b1 24.2\/75.4 \u00b1 14.7 mm Hg by the \u2018routine\u2019 method. A 1 SD increase in systolic BP increased the hazard ratio (HR) of the composite end-point by 1.16 (95% CI 0.89\u20131.50) for routine BP, 1.57 (95% CI 1.19\u20132.09) for standardized BP, 1.66 (95% CI 1.27\u20132.17) for home BP, and 1.42 (95% CI 1.10\u20131.84) for 24-hour ambulatory BP recording. The HR of the composite end-point was only significant for hypertension defined by 24-hour ambulatory BP monitoring (HR 2.22 (95% CI 1.23\u20134.01)). Adjusted for the propensity scores, BP measured by the ambulatory technique was not an independent predictor of cardiovascular events. Non-dipping was associated with increased cardiovascular risk, but not when adjusted for other risk factors. <i>Conclusion:<\/i> Risk factors that differentiate hypertension or non-dipping appear to confer a cardiovascular risk in CKD.<\/jats:p>","DOI":"10.1159\/000097366","type":"journal-article","created":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T17:37:54Z","timestamp":1164821874000},"page":"503-510","source":"Crossref","is-referenced-by-count":100,"title":["Blood Pressure Recordings within and outside the Clinic and Cardiovascular Events in Chronic Kidney Disease"],"prefix":"10.1159","volume":"26","author":[{"given":"Rajiv","family":"Agarwal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Andersen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,12,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161%2F01.HYP.0000152079.04553.2c"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa022273"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053%2Fj.ajkd.2005.02.015"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ki.5000247"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038%2Fsj.ki.5000081"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161%2F01.CIR.0000139860.33974.28"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161%2F01.CIR.0000133312.96477.48"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161%2F01.HYP.0000178102.85718.66"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2888%2992867-X"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097%2F00041552-200209000-00006"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.288.19.2421"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2805%2971082-5"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2802%2911911-8"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2804%2916456-8"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1523-1755.2005.00527.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097%2F00041552-200111000-00009"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097%2F00004872-199816060-00002"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097%2F00004872-200305000-00001"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.289.19.2560"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093%2Fndt%2F18.3.563"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1053%2Fajkd.2000.19100"}],"container-title":["American Journal of Nephrology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/97366","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/97366","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:02:53Z","timestamp":1745463773000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000097366"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":21,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2006,12,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000097366","archive":["Portico"],"relation":{},"ISSN":["0250-8095","1421-9670"],"issn-type":[{"value":"0250-8095","type":"print"},{"value":"1421-9670","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006]]}}}