{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T21:12:57Z","timestamp":1790802777085,"version":"4.1.0"},"reference-count":11,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T00:00:00Z","timestamp":1164758400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2006,11,29]],"date-time":"2006-11-29T00:00:00Z","timestamp":1164758400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nephron Clin Pract"],"abstract":"<jats:p>&lt;i&gt;Background\/Aims:&lt;\/i&gt; In patients with primary renal diseases the current knowledge of hyperglycemia associated with corticosteroid therapy is limited. We therefore examined the prevalence and risk factors of glucocorticoid-induced diabetes mellitus (DM) in primary renal diseases. &lt;i&gt;Methods:&lt;\/i&gt; Patients were recruited with primary renal diseases who were started on corticosteroids between April 2002 and June 2005. In patients with DM, an impaired fasting glucose level and\/or positive urinary glucose analyses before corticosteroids therapy were excluded. &lt;i&gt;Results:&lt;\/i&gt; During corticosteroid therapy (initial dose: prednisolone 0.75 \u00b1 0.10 mg\/kg\/day), DM was newly diagnosed in 17 (40.5%) of 42 patients. All of the 17 patients were diagnosed as having DM by postprandial hyperglycemia at 2 h after lunch, although they had normal fasting blood glucose levels. Age (OR 1.40, 95% CI 1.06\u20131.84) and body mass index (OR 1.87, 95% CI 1.03\u20133.38) were determined as independent risk factors for glucocorticoid-induced DM. &lt;i&gt;Conclusion:&lt;\/i&gt; Over 40% of patients with primary renal disease developed DM during treatment with corticosteroids. A high age and high body mass index are the independent risk factors for glucocorticoid-induced DM. 24-hour urinary glucose analyses and postprandial plasma glucose are useful for detecting glucocorticoid-induced DM.<\/jats:p>","DOI":"10.1159\/000097598","type":"journal-article","created":{"date-parts":[[2006,12,1]],"date-time":"2006-12-01T07:39:49Z","timestamp":1164958789000},"page":"c54-c57","source":"Crossref","is-referenced-by-count":103,"title":["Glucocorticoid-Induced Diabetes Mellitus: Prevalence and Risk Factors in Primary Renal Diseases"],"prefix":"10.1159","volume":"105","author":[{"given":"T.","family":"Uzu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Harada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Sakaguchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Kanasaki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"K.","family":"Isshiki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Araki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Sugiomoto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Koya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Haneda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Kashiwagi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Yamauchi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2006,11,29]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0889-8529%2805%2970271-1"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9343%2894%2990131-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1681%2FASN.2004070580"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001%2Farchinte.154.1.97"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10157-005-0346-y"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0889-857X%2805%2970083-1"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1399-0012.2002.02059.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038%2Fnm1278"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiabetes.47.3.345"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.2337%2Fdiacare.24.6.983"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159%2F000069534"}],"container-title":["Nephron Clinical Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/97598","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/97598","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,23]],"date-time":"2025-04-23T23:05:05Z","timestamp":1745449505000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000097598"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006,11,29]]},"references-count":11,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2007,1,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000097598","archive":["Portico"],"relation":{},"ISSN":["1660-2110"],"issn-type":[{"value":"1660-2110","type":"electronic"}],"subject":[],"published":{"date-parts":[[2006,11,29]]}}}