{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T14:40:59Z","timestamp":1766155259706,"version":"3.40.4"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Caries Res"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>The Trial to Enhance Elderly Teeth Health (TEETH) was designed to test the impact of regular rinsing with a 0.12% chlorhexidine (CHX) solution on tooth loss, and the causes of tooth loss (caries, periodontal disease and trauma) were also investigated. This paper reports on the effectiveness of a 0.12% CHX solution for controlling caries using a tooth surface (coronal and root) survival analysis. A total of 1,101 low income elders in Seattle (United States) and Vancouver (Canada), aged 60\u201375 years, were recruited for a double-blind clinical trial and assigned to either a CHX (n = 550) or a placebo (n = 551) mouth rinse. Subjects alternated between daily rinsing for 1 month, followed by weekly rinsing for 5 months. All sound coronal and root surfaces at baseline were followed annually for up to 5 years. At each follow-up examination, those tooth surfaces with caries, restored, or extracted were scored as \u2018carious\u2019. The hazard ratio associated with CHX for a sound surface to become filled, decayed, or extracted was 0.87 for coronal surfaces (95% confidence interval: 0.71\u20131.14, p = 0.20) and 0.91 for root surfaces (95% confidence interval: 0.73\u20131.14, p = 0.41). These findings suggest that regular rinsing with CHX does not have a substantial effect on the preservation of sound tooth structure in older adults.<\/jats:p>","DOI":"10.1159\/000098041","type":"journal-article","created":{"date-parts":[[2007,2,7]],"date-time":"2007-02-07T10:24:44Z","timestamp":1170843884000},"page":"93-101","source":"Crossref","is-referenced-by-count":31,"title":["Chlorhexidine and Preservation of Sound Tooth Structure in Older Adults"],"prefix":"10.1159","volume":"41","author":[{"given":"C.C.L.","family":"Wyatt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Maupome","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.P.","family":"Hujoel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.I.","family":"MacEntee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.R.","family":"Persson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.E.","family":"Persson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.A.","family":"Kiyak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,2,9]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1741-2358.2000.00067.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.1997.tb00898.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345950740110301"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000262365"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177%2F154405910408300810"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177%2F154405910508400806"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1754-4505.2005.tb01419.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345010800020501"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345970760040801"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345970760040701"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-051X.1998.tb02448.x"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016%2F0030-4220%2891%2990161-5"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2307%2F2291134"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.1997.tb00899.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0749-3797%2802%2900449-X"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159%2F000077758"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1177%2F00220345960750020901"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1600-0528.2004.00176.x"}],"container-title":["Caries Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/98041","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/98041","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:27:12Z","timestamp":1745461632000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000098041"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2007,2,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000098041","archive":["Portico"],"relation":{},"ISSN":["0008-6568","1421-976X"],"issn-type":[{"type":"print","value":"0008-6568"},{"type":"electronic","value":"1421-976X"}],"subject":[],"published":{"date-parts":[[2007]]}}}