{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:13:02Z","timestamp":1777947182708,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[1995,11,6]],"date-time":"1995-11-06T00:00:00Z","timestamp":815616000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[1995,11,6]],"date-time":"1995-11-06T00:00:00Z","timestamp":815616000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Stereotact Funct Neurosurg"],"abstract":"<jats:p>Between April 1992 and March 1994, 48 patients with skull base meningiomas were treated at our department. The age of these patients ranged from 10 to 76 years. The male:female ratio was 1:3. Thirty-seven of these patients had primary open surgery for partial removal and subsequent radiosurgical treatment. In 1 patient a recurrent meningioma after so-called total microsurgical removal was treated radiosurgicam Radiosurgery was performed as a primary treatment in 11 patients. The mean tumor volume was 13.7 cm3 (range: 0.8\u201382 cm3). These tumor volumes could be covered by mean isodose volumes of 44% (range: 30\u201370%) and were treated by a mean dose of 15 Gy (range: 8\u201325 Gy) at the tumor border. One patient underwent radiosurgery with a staged treatment protocol with a 4.6-month interval. In 37 patients, a total of 102 follow-up scans were available. The remaining 11 patients have not been included in the postradiosurgical evaluation, since the observation time was either too short or the patients were lost to follow-up. The mean interval between Gamma Knife treatment and the last follow-up scan was 12 months, with a range from 2.3 to 22.7 months. Follow-up imaging (CT, MRI or both) revealed a decreased volume of the tumor in 9 cases (24%). In 25 cases (68%), tumor progression was stopped, and in 3 cases (8%) increased tumor volumes could be observed (2 patients with malignant meningiomas). In 3 cases marked central tumor necrosis was seen. Neurological follow-up examinations (n = 38 patients) showed a stable neurological status in 74%, ameliorated status in 13 % and worsening in 13 % of the patients.<\/jats:p>","DOI":"10.1159\/000098760","type":"journal-article","created":{"date-parts":[[2017,4,18]],"date-time":"2017-04-18T17:21:55Z","timestamp":1492536115000},"page":"11-18","source":"Crossref","is-referenced-by-count":14,"title":["Stereotactic Radiosurgery of Skull Base Meningiomas"],"prefix":"10.1159","author":[{"given":"G.","family":"Pendl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.","family":"Schr\u00f6ttner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.M.","family":"Friehs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Feichtinger","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[1995,11,6]]},"container-title":["Stereotactic and Functional Neurosurgery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000098760","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T22:26:04Z","timestamp":1777760764000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000098760"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1995,11,6]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000098760","archive":["Portico"],"relation":{},"ISSN":["1011-6125","1423-0372"],"issn-type":[{"value":"1011-6125","type":"print"},{"value":"1423-0372","type":"electronic"}],"subject":[],"published":{"date-parts":[[1995,11,6]]}}}