{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,31]],"date-time":"2025-10-31T07:08:18Z","timestamp":1761894498867,"version":"3.40.4"},"reference-count":9,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urol Int"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; In nonseminomatous testicular cancer patients with normal serum tumor markers and no distant metastasis, postorchiectomy surgery is a valid treatment option if the disease extension into the retroperitoneum is not advanced. We assessed the ability of ultrasound (US) to exclude the presence of bulky retroperitoneal disease. &lt;i&gt;Materials and Methods:&lt;\/i&gt; One hundred and forty testicular cancer patients underwent US and computed tomography (CT) of the retroperitoneum. US results were analyzed using three cutoffs: 5 cm (conventional staging), 3 cm (based on the minimal sonographical dimension of actual bulky disease) and 0 cm (\u2018clean retroperitoneum\u2019 or any detectable nodes), and were compared with CT data using the 5-cm cutoff (\u2018gold standard\u2019). &lt;i&gt;Results:&lt;\/i&gt; The sensitivity, specificity, overall accuracy, positive and negative predictive values of US in detecting of bulky retroperitoneum for the 5-cm cutoff were 83, 96, 93, 88 and 94%, for the 3-cm cutoff 100, 91, 94, 80 and 100%, and for the 0-cm cutoff 100, 66, 74, 49 and 100%, respectively. &lt;i&gt;Conclusions:&lt;\/i&gt; In stage I and IIA\/B marker-negative nonseminomas if the treatment strategy is surgery, US may facilitate the selection process; the report of a clean retroperitoneum safely excludes the presence of bulky disease and may be an indication for lymphadenectomy, although in case of positive findings a CT should be performed.<\/jats:p>","DOI":"10.1159\/000099342","type":"journal-article","created":{"date-parts":[[2007,3,30]],"date-time":"2007-03-30T10:01:34Z","timestamp":1175248894000},"page":"226-229","source":"Crossref","is-referenced-by-count":10,"title":["Is Ultrasound of the Retroperitoneum a Valuable Staging Method in Selecting Testicular Cancer Patients for Primary Retroperitoneal Lymph Node Dissection?"],"prefix":"10.1159","volume":"78","author":[{"given":"Zaza","family":"Mezvrishvili","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zaza","family":"Tchanturaia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tengiz","family":"Toidze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nino","family":"Turmanidze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maka","family":"Kekelidze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Laurent","family":"Managadze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,4,4]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2887%2990889-0"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1464-410X.1999.00869.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-5347%2801%2961615-X"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM198712033172303"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097%2F00005392-199501000-00030"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1159%2F000020197"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1464-410X.1981.tb03162.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1159%2F000049759"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0022-5347%2801%2966778-8"}],"container-title":["Urologia Internationalis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/99342","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/99342","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:39:50Z","timestamp":1745462390000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000099342"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2007,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000099342","archive":["Portico"],"relation":{},"ISSN":["0042-1138","1423-0399"],"issn-type":[{"type":"print","value":"0042-1138"},{"type":"electronic","value":"1423-0399"}],"subject":[],"published":{"date-parts":[[2007]]}}}