{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T00:47:53Z","timestamp":1776127673371,"version":"3.50.1"},"reference-count":22,"publisher":"S. Karger AG","issue":"1","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Ann Nutr Metab"],"published-print":{"date-parts":[[2007]]},"abstract":"<i>Introduction:<\/i> Vitamin D is a vital element for bone health but the problem of vitamin D deficiency is underestimated in Hong Kong. <i>Methods:<\/i> Serum 25(OH)D and parathyroid hormone (PTH) levels were evaluated in 382 community dwelling Chinese adults >50 years for their relation with bone mineral density (BMD) and risks of osteoporotic fractures and falls. <i>Results:<\/i> The mean age of the subjects was 69 \u00b1 9 years. The mean 25(OH)D level was 28.3 \u00b1 10.8 ng\/ml with 62.8% of the subjects having levels <30 ng\/ml. 6.3% of the subjects had elevated PTH levels. A curvilinear relation between serum PTH and 25(OH)D was found, with PTH starting to increase when 25(OH)D level fell below 30 ng\/ml (r = \u20130.233, p < 0.05). Although subjects with vitamin D <30 ng\/ml had significantly lower BMD, only sex, age and PTH but not 25(OH)D were predictors of BMD at the spine and hip. Subjects with elevated PTH levels had a 2.92-fold increased risk of falls and 2.94-fold increased risk of fractures at the hip and spine. <i>Conclusions:<\/i> Vitamin D insufficiency and its complication of secondary hyperparathyroidism is common even in subtropical region and is an important risk factor for low bone mass, falls and fractures.<\/jats:p>","DOI":"10.1159\/000100822","type":"journal-article","created":{"date-parts":[[2007,3,14]],"date-time":"2007-03-14T09:53:04Z","timestamp":1173865984000},"page":"59-64","source":"Crossref","is-referenced-by-count":62,"title":["Prevalence and Impact of Vitamin D Insufficiency in Southern Chinese Adults"],"prefix":"10.1159","volume":"51","author":[{"given":"W.Z.M.","family":"Wat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.Y.Y.","family":"Leung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Tam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.W.C.","family":"Kung","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,3,15]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0140-6736%2805%2978933-9"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.274.21.1683"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.3.1212"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199803193381201"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1210%2Fer.22.4.477"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2FS0889-8529%2802%2900063-4"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00198-005-1867-7"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136%2Fpgmj.60.707.589"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186%2F1471-2458-4-38"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2FBF01623759"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136%2Fjech.52.10.631"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.86.11.5217"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007%2Fs001980050254"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00198-004-1778-z"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007%2Fs001980050030"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1530%2Feje.0.1430673"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2004-2364"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2002-020636"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1007%2Fs001980050162"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2003-031979"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2003-030604"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2003-031782"}],"container-title":["Annals of Nutrition and Metabolism"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/100822","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/100822","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:54:48Z","timestamp":1745463288000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000100822"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":22,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2007,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000100822","archive":["Portico"],"relation":{},"ISSN":["0250-6807","1421-9697"],"issn-type":[{"value":"0250-6807","type":"print"},{"value":"1421-9697","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}