{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T08:20:25Z","timestamp":1791188425781,"version":"4.1.0"},"reference-count":6,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Hidradenitis suppurativa (Verneuil\u2019s disease) is a chronic suppurative dermatosis involving apocrine glands with a severe impact on the quality of life, which is enhanced by the fact that the drugs usually prescribed are poorly effective. &lt;i&gt;Objective:&lt;\/i&gt; We discuss a new therapeutic approach based on zinc salts. &lt;i&gt;Methods:&lt;\/i&gt; We performed a pilot study on 22 patients, mainly from grade I or II in Hurley\u2019s classification. All included patients had previously been prescribed a treatment (antibiotic, isotretinoin, surgery or anti-androgens), which was inefficient. They were then treated with 90 mg of zinc gluconate per day (15 mg zinc per Rubozinc\u00ae capsule). &lt;i&gt;Results:&lt;\/i&gt; We observed a clinical response in all patients, with 8 complete remissions (CR) and 14 partial remissions (PR). When CR was obtained, the treatment was progressively decreased (average of 3.5 capsules\/day); 4\/22 patients experienced side-effects, mainly gastro-intestinal. &lt;i&gt;Conclusion: &lt;\/i&gt;Zinc salts could provide a new therapeutic alternative for the treatment of hidradenitis suppurativa.<\/jats:p>","DOI":"10.1159\/000100883","type":"journal-article","created":{"date-parts":[[2007,4,25]],"date-time":"2007-04-25T11:59:56Z","timestamp":1177502396000},"page":"325-327","source":"Crossref","is-referenced-by-count":114,"title":["Hidradenitis Suppurativa and Zinc: A New Therapeutic Approach"],"prefix":"10.1159","volume":"214","author":[{"given":"Anabelle","family":"Brocard","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anne-Chantal","family":"Knol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir","family":"Khammari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brigitte","family":"Dr\u00e9no","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2007,4,27]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2896%2990321-7"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1159%2F000096194"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.1990.tb06264.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000051728"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1080%2F000155598441459"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111%2F1523-1747.ep12606985"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/100883","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/100883","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:55:23Z","timestamp":1745463323000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000100883"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":6,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2007,4,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000100883","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}