{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,20]],"date-time":"2026-04-20T17:05:51Z","timestamp":1776704751928,"version":"3.51.2"},"reference-count":9,"publisher":"S. Karger AG","issue":"3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Blood Purif"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Backgrounds:&lt;\/i&gt; To study calcium homeostasis during citrate-based compared to nadroparin-based CVVH in critically-ill patients with acute renal failure. &lt;i&gt;Methods:&lt;\/i&gt; 11 patients were observed during citrate anticoagulation, 9 with nadroparin and 10 controls. Citrate was chosen for patients with active or at risk for bleeding. &lt;i&gt;Results:&lt;\/i&gt; The controls had, at 24 h, a median serum iCa of 1.1 mmol\/l, the citrate group 0.87 mmol\/l and the nadroparin group 1.1 mmol\/l (citrate vs. control p = 0.001, citrate vs. nadroparin p = 0.002). At 48 h, iCa was not significantly different anymore. Ca balance was negative for the citrate group in contrast to the nadroparin group (p = 0.012). Median serum PTH was higher (30.0 pmol\/l vs. 6.5 pmol\/l, p = 0.003) in the citrate group. &lt;i&gt;Conclusion:&lt;\/i&gt; With a relative low target-serum-iCa (0.8\u20130.9 mmol\/l) citrate CVVH-treated patients had a negative daily calcium balance and a temporarily lower iCa level resulting in an enhanced PTH response in comparison to nadroparin.<\/jats:p>","DOI":"10.1159\/000101853","type":"journal-article","created":{"date-parts":[[2007,4,20]],"date-time":"2007-04-20T10:28:54Z","timestamp":1177064934000},"page":"267-273","source":"Crossref","is-referenced-by-count":15,"title":["An Observational Study on the Effects of Nadroparin-Based and Citrate-Based Continuous Venovenous Hemofiltration on Calcium Metabolism"],"prefix":"10.1159","volume":"25","author":[{"given":"Peter H.J.","family":"van der Voort","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonja R.","family":"Postma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W. Peter","family":"Kingma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"E. Christiaan","family":"Boerma","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Loek J.M.","family":"de Heide","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andries J.","family":"Bakker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,4,19]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007%2Fs001340050953"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1523-1755.2005.00342.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00134-003-2047-x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2FS0272-6386%2899%2970249-0"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1677%2Fjoe.1.06057"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1213%2F01.ANE.0000132780.87036.F5"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1097%2F00003246-200001000-00015"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1210%2Fjc.2003-030358"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1378%2Fchest.114.4.1122"}],"container-title":["Blood Purification"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/101853","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/101853","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T03:06:29Z","timestamp":1745463989000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000101853"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":9,"journal-issue":{"issue":"3","published-online":{"date-parts":[[2007,7,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000101853","archive":["Portico"],"relation":{},"ISSN":["0253-5068","1421-9735"],"issn-type":[{"value":"0253-5068","type":"print"},{"value":"1421-9735","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}