{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T14:10:44Z","timestamp":1761487844161,"version":"3.40.4"},"reference-count":8,"publisher":"S. Karger AG","issue":"4","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Med Princ Pract"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; To report a case of brucella infection presenting with thrombotic thrombocytopenic purpura (TTP) that responded well to plasma and antimicrobial treatment infusion. &lt;i&gt;Case Presentation and Intervention:&lt;\/i&gt; A 51-year-old man with moderate confusion, depressed mood and dysarthria was admitted. He was chronically ill, with fever (38.5\u00b0C), anemia, jaundice and petechial-purpuric skin lesions. Neurological examination revealed diminished consciousness with a Glasgow coma scale score of 7 and +1 neck rigidity. The hemoglobin and platelet counts were decreased and reticulocyte index, erythrocyte sedimentation rate, as well as serum lactate dehydrogenase and renal dysfunction were elevated. TTP was a possible diagnosis and the patient responded well to plasma infusion and antimicrobial treatment. &lt;i&gt;Conclusion:&lt;\/i&gt; This report shows that therapy of underlying infection together with plasma infusion may be a successful treatment option for brucellosis-induced TTP.<\/jats:p>","DOI":"10.1159\/000102159","type":"journal-article","created":{"date-parts":[[2007,6,1]],"date-time":"2007-06-01T12:25:47Z","timestamp":1180700747000},"page":"324-326","source":"Crossref","is-referenced-by-count":11,"title":["Thrombotic Thrombocytopenic Purpura in a Patient with Brucella Infection Is Highly Responsive to Combined Plasma Infusion and Antimicrobial Therapy"],"prefix":"10.1159","volume":"16","author":[{"given":"Fuat","family":"Erdem","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130lhami","family":"Kiki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mehmet","family":"G\u00fcndo\u011fdu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Kaya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,6,6]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1538-7836.2005.01350.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002770100334"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ijantimicag.2005.06.001"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMra020528"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9343%2889%2990011-9"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jinf.2004.10.004"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.micinf.2004.04.012"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ijid.2004.07.009"}],"container-title":["Medical Principles and Practice"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/102159","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/102159","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:30:34Z","timestamp":1745461834000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000102159"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":8,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2007,6,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000102159","archive":["Portico"],"relation":{},"ISSN":["1011-7571","1423-0151"],"issn-type":[{"type":"print","value":"1011-7571"},{"type":"electronic","value":"1423-0151"}],"subject":[],"published":{"date-parts":[[2007]]}}}