{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:28:14Z","timestamp":1789532894877,"version":"build-2803163510"},"reference-count":7,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Objective:&lt;\/i&gt; A fetus with large sac S1 myelomeningocele (MMC) but bilateral talipes prompted the question, \u2018Does the presence or size of an MMC sac affect postnatal leg function?\u2019 &lt;i&gt;Study Design:&lt;\/i&gt; An MMC database with prenatal, birth, and a minimum of 1-year follow-up evaluation was reviewed. All fetuses had in-utero MMC repair at 20 + 0 to 25 + 6 weeks at a single institution. Fifty-four fetuses had prenatal evaluation, with 48 children completing a birth and a 1-year evaluation of leg function. &lt;i&gt;Results:&lt;\/i&gt; An MMC sac was present in 38\/54 (70%) of fetuses evaluated in-utero and had been present in 35\/48 (73%) of children evaluated at 1 year of age. Although leg function evaluated at 1 year was better than expected in the \u2018no sac\u2019 group (p = 0.059), this did not reach statistical significance. &lt;i&gt;Conclusion:&lt;\/i&gt; The presence of an MMC sac may increase postnatal lower limb morbidity.<\/jats:p>","DOI":"10.1159\/000103294","type":"journal-article","created":{"date-parts":[[2007,6,7]],"date-time":"2007-06-07T13:48:53Z","timestamp":1181224133000},"page":"348-351","source":"Crossref","is-referenced-by-count":11,"title":["Does a Myelomeningocele Sac Compared to No Sac Result in Decreased Postnatal Leg Function following Maternal Fetal Surgery for Spina Bifida Aperta?"],"prefix":"10.1159","volume":"22","author":[{"given":"R. Douglas","family":"Wilson","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark P.","family":"Johnson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Bebbington","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alan W.","family":"Flake","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Holly L.","family":"Hedrick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leslie N.","family":"Sutton","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N. Scott","family":"Adzick","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2007,6,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1067%2FS0002-9378%2803%2900295-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001%2Fjama.282.19.1826"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320470528"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320210103"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320350316"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.109.3.409"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJM199103073241004"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/103294","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/103294","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:42:39Z","timestamp":1745462559000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000103294"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":7,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000103294","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"value":"1015-3837","type":"print"},{"value":"1421-9964","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}