{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:58:04Z","timestamp":1745470684925,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"5","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Fetal Diagn Ther"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Objectives:&lt;\/i&gt; To describe the molecular analysis through comparative genomic hybridization (CGH) of fetuses with gastroschisis, and to observe if this technique could improve the resolution of the conventional cytogenetic techniques. &lt;i&gt;Methods:&lt;\/i&gt; Amniotic analysis of fetuses with gastroschisis, using both conventional (G-banding) and molecular (CGH) cytogenetics assays. &lt;i&gt;Results:&lt;\/i&gt; All of the seven fetuses studied displayed a normal G-band karyotype. Six fetuses displayed a normal disomic profile through CGH and one sample has displayed ish cgh enh 3q26\u2192qter result (ICSN). The fetus with this imbalance of chromosome 3 was re-classified as a ruptured omphalocele, instead of gastroschisis, after birth. &lt;i&gt;Conclusions:&lt;\/i&gt; The molecular investigation through CGH technique can improve the resolution of the conventional karyotye analysis in cases of abdominal wall defects.<\/jats:p>","DOI":"10.1159\/000103297","type":"journal-article","created":{"date-parts":[[2007,6,7]],"date-time":"2007-06-07T13:48:53Z","timestamp":1181224133000},"page":"361-364","source":"Crossref","is-referenced-by-count":4,"title":["Prenatal Genomic Profiling of Abdominal Wall Defects through Comparative Genomic Hybridization: Perspectives for a New Diagnostic Tool"],"prefix":"10.1159","volume":"22","author":[{"given":"Juliana Karina Ruiz","family":"Heinrich","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabela Nelly","family":"Machado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luciana","family":"Vivas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Ot\u00edlia","family":"Bianchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kleber","family":"Cursino Andrade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Louren\u00e7o","family":"Sbragia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ricardo","family":"Barini","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,6,5]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.168.3937.1356"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.1359641"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1126%2Fscience.273.5274.494"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159%2F000089062"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.1290"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10024-005-0041-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.1179"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002%2Fpd.1187"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016%2FS0306-5456%2800%2900139-X"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097%2F01.gco.0000162188.99219.04"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320580218"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2Fajmg.1320440528"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053%2Fjpsu.2001.23961"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002%2Fbdra.10113"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097%2F01.GIM.0000133919.68912.A3"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1034%2Fj.1399-0004.2003.00159.x"}],"container-title":["Fetal Diagnosis and Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/103297","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/103297","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:42:41Z","timestamp":1745462561000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000103297"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":16,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000103297","archive":["Portico"],"relation":{},"ISSN":["1015-3837","1421-9964"],"issn-type":[{"type":"print","value":"1015-3837"},{"type":"electronic","value":"1421-9964"}],"subject":[],"published":{"date-parts":[[2007]]}}}