{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,5]],"date-time":"2026-05-05T02:11:24Z","timestamp":1777947084189,"version":"3.51.4"},"reference-count":0,"publisher":"S. Karger AG","license":[{"start":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T00:00:00Z","timestamp":1180483200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"},{"start":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T00:00:00Z","timestamp":1180483200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/karger.com\/pages\/terms-and-conditions"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Confin Neurol"],"abstract":"<jats:p>Four cases of infantile neuroaxonal dystrophy (a familial progressive disorder of the central nervous system) are presented with clinical and pathological findings. The clinical picture is characterized by a fairly normal development of the children up to about one year of age when a standstill and regression of motor and psychic development became apparent. Some children develop a marked generalized hypotonia, others a spasticity. Optic nerve atrophy is usually another early clinical sign. Pathologically a marked cerebellar atrophy and the occurrence of so-called ''speroid bodies'' are characteristic; the latter are signs of neuroaxonal degeneration. One of the patients presented here showed extrapyramidal signs which so far have not been seen in infantile neuroaxonal dystrophy.<\/jats:p>","DOI":"10.1159\/000103445","type":"journal-article","created":{"date-parts":[[2007,5,30]],"date-time":"2007-05-30T08:08:42Z","timestamp":1180512522000},"page":"409-422","source":"Crossref","is-referenced-by-count":3,"title":["Infantile Neuroaxonal Dystrophy"],"prefix":"10.1159","author":[{"given":"R.","family":"Kohn","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Mundel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Wallis","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,5,30]]},"container-title":["Confinia Neurologica"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/103445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/karger.com\/article-pdf\/doi\/10.1159\/000103445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,2]],"date-time":"2026-05-02T21:55:37Z","timestamp":1777758937000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000103445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5,30]]},"references-count":0,"URL":"https:\/\/doi.org\/10.1159\/000103445","archive":["Portico"],"relation":{},"ISSN":["0010-5678","2571-7227"],"issn-type":[{"value":"0010-5678","type":"print"},{"value":"2571-7227","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007,5,30]]}}}