{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:47:41Z","timestamp":1761630461302,"version":"3.40.4"},"reference-count":19,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; Topical imiquimod is a new immunomodulator agent approved for genital warts, actinic keratosis (AK) or carcinoma, occurring in immunocompetent patients. &lt;i&gt;Objectives:&lt;\/i&gt; This study aimed to assess the safety and efficacy of imiquimod for the treatment of warts, AK and bowenoid papulosis (BP) in transplant patients. &lt;i&gt;Methods:&lt;\/i&gt; 24 transplant patients (18 kidney, 4 kidney-pancreas and 2 heart) were included in this retrospective study conducted between June 2000 and February 2003 at the department of dermatology of 3 hospitals. Imiquimod cream was applied 3 times a week over a median period of 9 weeks. &lt;i&gt;Results:&lt;\/i&gt; Graft function was not altered under therapy. Local tolerance was excellent. Complete responses were observed in 1 patient (1\/12) with cutaneous warts and 1 (1\/6) with AK. Two patients of 3 with BP had total clearance of their lesions. Partial responses were observed in 3 of the 6 AK-treated patients, 5 of 12 patients with cutaneous warts and 1 of 2 patients with anogenital warts. &lt;i&gt;Conclusions:&lt;\/i&gt; Imiquimod 5% cream is a promising, well-tolerated therapy for warts, AK and BP in transplant recipients.<\/jats:p>","DOI":"10.1159\/000104264","type":"journal-article","created":{"date-parts":[[2007,8,8]],"date-time":"2007-08-08T15:14:40Z","timestamp":1186586080000},"page":"130-133","source":"Crossref","is-referenced-by-count":16,"title":["5% Topical Imiquimod Tolerance in Transplant Recipients"],"prefix":"10.1159","volume":"215","author":[{"given":"Lilia","family":"Ben M\u2019barek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amel","family":"Mebazaa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sylvie","family":"Euvrard","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Camille","family":"Frances","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eric","family":"Thervet","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrice","family":"Morel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suzanne","family":"Menasch\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christophe","family":"Legendre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Celeste","family":"Lebbe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,8,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1529-8019.2005.05008.x"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2230.28.s1.6.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2001.04197.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2005.06322.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.141.8.985"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00002030-199912030-00011"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1365-2133.2006.07233.x"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1524-4725.2001.00149.x"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097%2F01.TP.0000113445.02908.06"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2003.12.010"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.jaad.2004.02.022"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1542%2Fpeds.112.1.e73"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080%2F00015550260132550"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00404-002-0385-5"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1159%2F000095039"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1258%2F0956462021925180"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1258%2F095646204322637191"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1046%2Fj.1365-2133.2000.03777.x"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1159%2F000063909"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104264","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104264","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:53:08Z","timestamp":1745463188000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000104264"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":19,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000104264","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"type":"print","value":"1018-8665"},{"type":"electronic","value":"1421-9832"}],"subject":[],"published":{"date-parts":[[2007]]}}}