{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,31]],"date-time":"2026-07-31T23:15:23Z","timestamp":1785539723181,"version":"3.56.0"},"reference-count":18,"publisher":"S. Karger AG","issue":"2","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Dermatology"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>The treatment of severe lymphedema is a difficult challenge. We performed lymphaticovenular anastomosis on two patients with secondary skin lesions of chronic lymphedema; one patient exhibited acquired lymphangioma circumscriptum of the vulva and the other presented elephantiasis nostras verrucosa of the lower leg. Both patients obtained a remarkable improvement in skin lesions and also in the reduction of lymphedema of the lower extremity. During a 6-month-follow-up period, constant reduction in the circumference of the lower extremities without exacerbation of skin lesions was achieved in both patients. Lymphaticovenular anastomosis is a useful surgical treatment for secondary lymphedema in the lower extremities. In addition, this surgical treatment is effective for secondary lesions of lymphedema, including acquired lymphangioma circumscriptum and elephantiasis nostras verrucosa.<\/jats:p>","DOI":"10.1159\/000104267","type":"journal-article","created":{"date-parts":[[2007,8,8]],"date-time":"2007-08-08T15:14:40Z","timestamp":1186586080000},"page":"147-151","source":"Crossref","is-referenced-by-count":11,"title":["Successful Treatment with Lymphaticovenular Anastomosis for Secondary Skin Lesions of Chronic Lymphedema"],"prefix":"10.1159","volume":"215","author":[{"given":"Sei-ichiro","family":"Motegi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atsushi","family":"Tamura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Etsuko","family":"Okada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yayoi","family":"Nagai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osamu","family":"Ishikawa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"127","published-online":{"date-parts":[[2007,8,8]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1177%2F000331978503600306"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097%2F00006534-197006000-00003"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800651202"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007%2Fs00595-005-3111-7"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007%2Fs10147-005-0518-5"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097%2F00006534-199602000-00018"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2006-947150"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097%2F01.sap.0000120319.89926.07"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055%2Fs-2003-40575"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.101.2.230"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2Fj.ejogrb.2005.02.023"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002%2Fbjs.1800730724"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1023%2FB%3AUROL.0000034668.75841.c2"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001%2Farchderm.108.6.832"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1524-4725.2004.30267.x"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1177%2F000331978803900206"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016%2FS0190-9622%2884%2980343-6"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159%2F000090649"}],"container-title":["Dermatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104267","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104267","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:53:10Z","timestamp":1745463190000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000104267"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":18,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000104267","archive":["Portico"],"relation":{},"ISSN":["1018-8665","1421-9832"],"issn-type":[{"value":"1018-8665","type":"print"},{"value":"1421-9832","type":"electronic"}],"subject":[],"published":{"date-parts":[[2007]]}}}