{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T04:58:39Z","timestamp":1745470719026,"version":"3.40.4"},"reference-count":16,"publisher":"S. Karger AG","issue":"2-3","license":[{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"},{"start":{"date-parts":[[2007,1,1]],"date-time":"2007-01-01T00:00:00Z","timestamp":1167609600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.karger.com\/Services\/SiteLicenses"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Cerebrovasc Dis"],"published-print":{"date-parts":[[2007]]},"abstract":"<jats:p>&lt;i&gt;Background:&lt;\/i&gt; We aimed to evaluate the prognostic value of myocardial perfusion gated SPECT in patients with symptomatic intracranial large-artery atherosclerosis (ILA). &lt;i&gt;Methods:&lt;\/i&gt; Seventy-two consecutive first-ever symptomatic ILA patients without known heart disease underwent a stress myocardial perfusion gated SPECT, and long-term follow-up was conducted thereafter. &lt;i&gt;Results:&lt;\/i&gt; During an average follow-up of 15.2 \u00b1 9 months, 9 patients (13.8%) presented major coronary events (CEs). Survival analyses (Kaplan-Meier and Cox regression) identified presence of moderate-to-severe myocardial perfusion defects (log rank p = 0.004) and ejection fraction &lt;50% (p = 0.014) as predictors of future CEs. Neurovascular ischemic events were not predicted by SPECT variables. &lt;i&gt;Conclusion:&lt;\/i&gt; Myocardial perfusion scintigraphy predicts future CEs in patients with symptomatic ILA and may be helpful to guide therapeutic strategies in this subgroup of stroke patients.<\/jats:p>","DOI":"10.1159\/000104486","type":"journal-article","created":{"date-parts":[[2007,6,29]],"date-time":"2007-06-29T09:43:10Z","timestamp":1183110190000},"page":"247-254","source":"Crossref","is-referenced-by-count":3,"title":["Prognostic Value of Myocardial Perfusion Gated SPECT in Patients with Symptomatic Intracranial Large-Artery Atherosclerosis"],"prefix":"10.1159","volume":"24","author":[{"given":"J.","family":"Candell-Riera","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.F.","family":"Arenillas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Romero-Farina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"Aguad\u00e9-Bruix","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"de Le\u00f3n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Castell-Conesa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A.","family":"Molina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Rovira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"\u00c1lvarez-Sab\u00edn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"127","published-online":{"date-parts":[[2007,6,28]]},"reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1161%2Fhs1201.099652"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000090125.28466.E2"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.17.6.1098"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016%2F0002-9149%2892%2990930-W"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.27.11.1974"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000089920.93927.A7"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161%2F01.STR.0000166045.12976.af"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016%2FS0735-1097%2896%2900562-1"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1161%2Fhc0402.102975"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007%2Fs002590000419"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016%2FS0735-1097%2802%2901707-2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1056%2FNEJMoa043033"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136%2Fbmj.1.5288.1293"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111%2Fj.1749-6632.1968.tb53849.x"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016%2FS0002-9149%2899%2900907-8"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016%2FS1071-3581%2805%2980003-0"}],"container-title":["Cerebrovascular Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104486","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.karger.com\/Article\/Pdf\/104486","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T02:55:35Z","timestamp":1745463335000},"score":1,"resource":{"primary":{"URL":"https:\/\/karger.com\/article\/doi\/10.1159\/000104486"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007]]},"references-count":16,"journal-issue":{"issue":"2-3","published-online":{"date-parts":[[2007,8,1]]}},"URL":"https:\/\/doi.org\/10.1159\/000104486","archive":["Portico"],"relation":{},"ISSN":["1015-9770","1421-9786"],"issn-type":[{"type":"print","value":"1015-9770"},{"type":"electronic","value":"1421-9786"}],"subject":[],"published":{"date-parts":[[2007]]}}}